TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
about
Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppressionAngiocrine functions of organ-specific endothelial cellsClinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathwayHematopoietic stem cell niche maintenance during homeostasis and regenerationHematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic AnemiaTgif1 regulates quiescence and self-renewal of hematopoietic stem cellsEndoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse modelsClonal-level responses of functionally distinct hematopoietic stem cells to trophic factors.TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.Genetic control of quiescence in hematopoietic stem cells.Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCsRe-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons.The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.Mechanisms of self-renewal in hematopoietic stem cells.Deconstructing the Complexity of TGFβ Signaling in Hematopoietic Stem Cells: Quiescence and Beyond.Extrinsic regulation of hematopoietic stem cells in development, homeostasis and diseases.Aberrant Activation of TGF-β in Subchondral Bone at the Onset of Rheumatoid Arthritis Joint DestructionExpression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy.p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells.Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability.[TGFβ contribution to hematopoietic regeneration after myelosuppressive chemotherapy].Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis.Genotoxicity kinetics in murine normoblasts as an approach for the in vivo action of difluorodeoxycytidine.The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis.TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis
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P2860
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@ast
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@en
type
label
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@ast
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@en
prefLabel
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@ast
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.
@en
P2093
P2860
P356
P1476
TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy
@en
P2093
Fabienne Brenet
Pouneh Kermani
Shahin Rafii
P2860
P304
P356
10.1084/JEM.20121610
P407
P577
2013-02-25T00:00:00Z