Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
about
Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloningZinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modificationsTargeted gene inactivation in zebrafish using engineered zinc-finger nucleasesProgress and prospects: zinc-finger nucleases as gene therapy agentsRapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modificationEnvironmental signal integration by a modular AND gateNuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingSpotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein familyProtein design: toward functional metalloenzymesHoming endonucleases: DNA scissors on a missionUnexpected failure rates for modular assembly of engineered zinc fingersDirected evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleasesProgramming cells: towards an automated 'Genetic Compiler'Proprietary science, open science and the role of patent disclosure: the case of zinc-finger proteinsMax-E47, a designed minimalist protein that targets the E-box DNA site in vivo and in vitro.Cysteine and histidine shuffling: mixing and matching cysteine and histidine residues in zinc finger proteins to afford different folds and function.Upregulation of endogenous HMOX1 expression by a computer-designed artificial transcription factor.Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.Design of a zinc finger protein binding a sequence upstream of the A20 gene.Design and construction of a double inversion recombination switch for heritable sequential genetic memory.Hybrids of the bHLH and bZIP protein motifs display different DNA-binding activities in vivo vs. in vitro.Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).ZifBASE: a database of zinc finger proteins and associated resourcesOligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arraysPositive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodiesSynthetic design of strong promotersDirected evolution of recombinase specificity by split gene reassemblyModular system for the construction of zinc-finger libraries and proteins.Specificity landscapes of DNA binding molecules elucidate biological functionZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.Light-inducible gene regulation with engineered zinc finger proteinsZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing.Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.Custom-designed zinc finger nucleases: what is next?Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Heritable targeted inactivation of myostatin gene in yellow catfish (Pelteobagrus fulvidraco) using engineered zinc finger nucleases.
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P2860
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
description
2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
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2006年论文
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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@ast
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@en
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@nl
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label
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@ast
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@en
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@nl
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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@ast
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@en
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@nl
P2860
P356
P1476
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
@en
P2093
Carlos F Barbas
Jeffrey G Mandell
P2860
P304
P356
10.1093/NAR/GKL209
P407
P433
Web Server issue
P577
2006-07-01T00:00:00Z