Modular system for the construction of zinc-finger libraries and proteins. - Wikidata - wikimedia - TriplyDB

Modular system for the construction of zinc-finger libraries and proteins.

Modular system for the construction of zinc-finger libraries and proteins.

http://www.wikidata.org/entity/Q33548644

about

Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription Genome-editing Technologies for Gene and Cell Therapy The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders Development and applications of CRISPR-Cas9 for genome engineering.Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering CRISPR-Cas systems for editing, regulating and targeting genomes Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.Assembly and validation of versatile transcription activator-like effector libraries Light-inducible gene regulation with engineered zinc finger proteins Programmable genetic switches to control transcriptional machinery of pluripotency.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.CRISPR/Cas9 for genome editing: progress, implications and challenges.Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos Genomic editing tools to model human diseases with isogenic pluripotent stem cells.Structure-guided reprogramming of serine recombinase DNA sequence specificity Highly active zinc-finger nucleases by extended modular assembly Advances in genome editing technology and its promising application in evolutionary and ecological studies Simultaneous screening and validation of effective zinc finger nucleases in yeast Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.Protein delivery using Cys2-His2 zinc-finger domains.Chimeric piggyBac transposases for genomic targeting in human cells Reprogramming cell fate with a genome-scale library of artificial transcription factors.Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells Transcriptional repression of Gata3 is essential for early B cell commitment.Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α.How to Train a Cell-Cutting-Edge Molecular Tools.Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Small-molecule regulators that mimic transcription factors Advances in targeted genome editing.Synthetic biology: advancing the design of diverse genetic systems Methods for studying the zebrafish brain: past, present and future.Off-target effects of engineered nucleases.Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells.Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering.Engineering designer nucleases with customized cleavage specificities.Induction of apoptosis in imatinib sensitive and resistant chronic myeloid leukemia cells by efficient disruption of bcr-abl oncogene with zinc finger nucleases.

P2860

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P2860

Modular system for the construction of zinc-finger libraries and proteins.

http://www.wikidata.org/entity/Q33548644

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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type

label

Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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prefLabel

Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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Modular system for the construction of zinc-finger libraries and proteins.

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P1433

Nature Protocols

P1476

Modular system for the construction of zinc-finger libraries and proteins.

@en

P2093

Carlos F Barbas

http://www.w3.org/2001/XMLSchema#string

Lauren J Schwimmer

http://www.w3.org/2001/XMLSchema#string

Lily Asawapornmongkol

http://www.w3.org/2001/XMLSchema#string

Roberta P Fuller

http://www.w3.org/2001/XMLSchema#string

Yongjun Ye

http://www.w3.org/2001/XMLSchema#string

P2860

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

Positive and negative regulation of endogenous genes by designed transcription factors

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

Chimeric recombinases with designed DNA sequence recognition

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

P2888

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791-810

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scholarly article

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10.1038/NPROT.2010.34

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4

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P478

5

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Beatriz Gonzalez

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2010-04-01T00:00:00Z

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232796763

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1021109615

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P698

20360772

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2855653

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