BetaKlotho is required for metabolic activity of fibroblast growth factor 21 - Wikidata - wikimedia - TriplyDB

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

http://www.wikidata.org/entity/Q24681531

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Circulating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional study Glycosylation of fibroblast growth factor receptor 4 is a key regulator of fibroblast growth factor 19-mediated down-regulation of cytochrome P450 7A1 betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21 Liver-specific activities of FGF19 require Klotho beta FGF21 N- and C-termini play different roles in receptor interaction and activation Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway Obesity is a fibroblast growth factor 21 (FGF21)-resistant state Endocrine fibroblast growth factors 15/19 and 21: from feast to famine Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response Fibroblast growth factor 21: from pharmacology to physiology Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease The FGF21-adiponectin axis in controlling energy and vascular homeostasis Fibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan Crosstalk Fibroblast Growth Factor Signaling in Metabolic Regulation Biological Role of Anti-aging Protein Klotho Inventing new medicines: The FGF21 story Regulation and function of the FGF23/klotho endocrine pathways Exploring mechanisms of FGF signalling through the lens of structural biology Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor FGF21 promotes metabolic homeostasis via white adipose and leptin in mice Fibroblast Growth Factor 21 Analogs for Treating Metabolic Disorders.Genetic insights into the mechanisms of Fgf signaling Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21 Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology A better anti-diabetic recombinant human fibroblast growth factor 21 (rhFGF21) modified with polyethylene glycol Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes FGF21 requires βklotho to act in vivo Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319 Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction Fundamentals of FGF19 & FGF21 action in vitro and in vivo Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism Exercise effects on perivascular adipose tissue: endocrine and paracrine determinants of vascular function.Therapeutic utilities of fibroblast growth factor 19.Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism Identification of Sp1 as a Transcription Activator to Regulate Fibroblast Growth Factor 21 Gene Expression.

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P2860

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

http://www.wikidata.org/entity/Q24681531

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@ast

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@en

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@nl

type

label

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@ast

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@en

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@nl

prefLabel

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@ast

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@en

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@nl

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PNAS.0701600104

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Proceedings of the National Academy of Sciences of the United States of America

P1476

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

@en

P2093

Animesh Nandi

http://www.w3.org/2001/XMLSchema#string

Anna V Eliseenkova

http://www.w3.org/2001/XMLSchema#string

Hiroshi Kurosu

http://www.w3.org/2001/XMLSchema#string

Kevin P Rosenblatt

http://www.w3.org/2001/XMLSchema#string

Makoto Kuro-o

http://www.w3.org/2001/XMLSchema#string

Masaya Yamamoto

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

FGF-21 as a novel metabolic regulator.

Suppression of aging in mice by the hormone Klotho

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Regulation of fibroblast growth factor-23 signaling by klotho

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7432-7437

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scholarly article

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373111

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10.1073/PNAS.0701600104

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P433

18

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104

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Moosa Mohammadi

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2007-04-23T00:00:00Z

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P5875

6375726

http://www.w3.org/2001/XMLSchema#string

P698

17452648

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P921

Fibroblast growth factor receptor 1

Fibroblast growth factor receptor 4

P932

1855074

http://www.w3.org/2001/XMLSchema#string