about
Glycosylation of fibroblast growth factor receptor 4 is a key regulator of fibroblast growth factor 19-mediated down-regulation of cytochrome P450 7A1Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlothoBile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expressionChronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 releaseFGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesisFGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation responseFibroblast Growth Factor Signaling in Metabolic RegulationBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerRegulation and function of the FGF23/klotho endocrine pathwaysBile acid metabolism and signalingBile acids as metabolic regulatorsRegulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted stateBile acid signaling in metabolic disease and drug therapyFibroblast growth factors as tissue repair and regeneration therapeutics.Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytesTargeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse modelsCharacterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolismFGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathwaysTherapeutic utilities of fibroblast growth factor 19.β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis.FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.Relevant use of Klotho in FGF19 subfamily signaling system in vivoIs fibroblast growth factor receptor 4 a suitable target of cancer therapy?Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cellsResearch resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.The human gallbladder secretes fibroblast growth factor 19 into bile: towards defining the role of fibroblast growth factor 19 in the enterobiliary tract.Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations.The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans.βKlotho suppresses tumor growth in hepatocellular carcinoma by regulating Akt/GSK-3β/cyclin D1 signaling pathway.Novel combination of sorafenib and celecoxib provides synergistic anti-proliferative and pro-apoptotic effects in human liver cancer cells.A Klothoβ variant mediates protein stability and associates with colon transit in irritable bowel syndrome with diarrhea.Fibroblast growth factor receptor 4 polymorphism is associated with liver cirrhosis in hepatocarcinomaMolecular basis of Klotho: from gene to function in agingKlotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma.Klotho-related Molecules Upregulated by Smoking Habit in Apparently Healthy Men: A Cross-sectional Study.Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.Fibroblast growth factors, old kids on the new block.
P2860
Q24294403-1DB27465-74D8-457E-AC45-FB173BB71617Q24306135-6B1F1C67-AEB1-4EAD-9FC6-FE4BA88064CEQ24336351-E8080C47-EF9A-4A68-BFFC-7B6D3BB01640Q24603434-CF95E296-9FBE-4AC9-8BB7-1D79D354EF93Q24617480-749028F3-3405-4DA7-AD02-D7FBC1683058Q24653481-CF34A811-5A4B-430D-A390-5CF4D05D86F4Q26772751-B03BE9C3-0ED4-4D61-B653-7085F467AF6DQ26800206-E576FF8A-BD75-450A-A4A5-F48AD19BD612Q26860470-3AEE47E5-D29C-4168-8EF9-594A8C4B728CQ27002873-F4427987-478F-4229-A72D-DF81B63EE9CBQ27022441-0D05EC77-DE94-43B2-A97B-0FF907255E23Q28070054-227C9C7C-12DC-4818-831A-E8CEE8A94353Q28244875-9D9EFBB2-2B25-414D-8606-5D7038595F99Q28272364-EC368056-F880-49C8-B428-106757B78D25Q28571616-ECA7741E-4B02-4C88-B26C-F49FDA5A419BQ28729944-AAA6BE28-95DD-4682-86C3-2A4E11263DEEQ28730955-8DFA9D62-8A80-464D-B3D3-426ACFF73DA5Q28741802-780CA87B-AF93-4FBB-99A9-47618E8C724BQ30407643-4794762B-8ABA-4C40-9BE2-0FFD9342EE84Q33578966-2686381A-DBD6-4ABB-A2C1-1198A86045FCQ33613352-B7B6AFD3-A295-459D-9C41-C6A0E59F3295Q33648263-792F7459-E2F1-450E-8F5E-46DCED180BA3Q33667883-511A2E22-210E-4BB2-87BB-9DE7E3EF98CCQ33751398-DB63FDAE-97A1-41D2-B55B-9857D7F71FA0Q34054829-11DB9357-F0A4-45C6-9F84-F96EB406B2F3Q34197301-C7BB388B-F0FB-483F-935A-B6494C4397C2Q34219880-F633682E-1904-4FDD-A693-71A34B24F394Q34258918-22EFF9A9-DCD8-46FE-AF1B-8FC906387E44Q34568579-74FF041E-726F-47A5-BBBE-0A8FAB41749EQ34576805-11CA3803-94F8-4B83-964C-C95040274805Q34775779-0897255E-0F15-4721-B8E3-B3BCE1E697D7Q35028313-DDB699B6-6983-45DA-945D-1823A56819A7Q35364559-64DB45E5-6121-41D0-82F9-F74A63694B03Q35441666-0A768C26-3282-4808-8A2C-D22B2576B135Q35991812-B4B09BF8-78AD-45B1-9702-1462719524FAQ36098882-02E7B078-D0B2-44ED-995F-DA569C1E7932Q36342875-E297B95C-65DA-4BF7-A808-97EFD6EE86FDQ36415805-F3B3C087-E37B-47CC-9035-733A31E6EB3FQ36832832-8FF5B1D5-823D-4DAA-B6B0-92D8BBEFDBB0Q36923642-E0740CAC-CF3D-4553-871C-36F5DA1DE91F
P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Liver-specific activities of FGF19 require Klotho beta
@ast
Liver-specific activities of FGF19 require Klotho beta
@en
Liver-specific activities of FGF19 require Klotho beta
@en-gb
Liver-specific activities of FGF19 require Klotho beta
@nl
type
label
Liver-specific activities of FGF19 require Klotho beta
@ast
Liver-specific activities of FGF19 require Klotho beta
@en
Liver-specific activities of FGF19 require Klotho beta
@en-gb
Liver-specific activities of FGF19 require Klotho beta
@nl
prefLabel
Liver-specific activities of FGF19 require Klotho beta
@ast
Liver-specific activities of FGF19 require Klotho beta
@en
Liver-specific activities of FGF19 require Klotho beta
@en-gb
Liver-specific activities of FGF19 require Klotho beta
@nl
P2093
P2860
P921
P356
P1476
Liver-specific activities of FGF19 require Klotho beta
@en
P2093
Benjamin C Lin
Craig Blackmore
Luc R Desnoyers
Manping Wang
P2860
P304
P356
10.1074/JBC.M704244200
P407
P577
2007-09-14T00:00:00Z