Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes
about
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activationPartitioning of Thy-1, GM1, and cross-linked phospholipid analogs into lipid rafts reconstituted in supported model membrane monolayers.Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cellsSpatial and temporal regulation of protein kinase D (PKD)Tetraspanins and Transmembrane Adaptor Proteins As Plasma Membrane Organizers-Mast Cell CaseCo-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signalingMembrane domain formation-a key factor for targeted intracellular drug deliveryThe spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imagingThe fusion peptide of Semliki Forest virus associates with sterol-rich membrane domains.A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylationUse of cyclodextrins to monitor transbilayer movement and differential lipid affinities of cholesterol.Cholesterol does not induce segregation of liquid-ordered domains in bilayers modeling the inner leaflet of the plasma membraneCross-correlation analysis of inner-leaflet-anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft componentsTernary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: nanoscopic domain formation driven by cholesterolLipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptorsRaft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signalingA novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptorRoles for SH2 and SH3 domains in Lyn kinase association with activated FcepsilonRI in RBL mast cells revealed by patterned surface analysis.Quantitative analysis of the fluorescence properties of intrinsically fluorescent proteins in living cellsStructure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation.Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays.Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling.Involvement of LAT, Gads, and Grb2 in compartmentation of SLP-76 to the plasma membraneNanoscopic lipid domain dynamics revealed by atomic force microscopyInteraction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase.Membrane raft association of CD47 is necessary for actin polymerization and protein kinase C theta translocation in its synergistic activation of T cells.Differential sensitivity to acute cholesterol lowering of activation mediated via the high-affinity IgE receptor and Thy-1 glycoprotein.Dynamics of putative raft-associated proteins at the cell surface.A versatile multimode microscope to probe and manipulate nanoparticles and biomolecules.Role of STARD4 in sterol transport between the endocytic recycling compartment and the plasma membrane.Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization.Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling.N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae.Cholesterol depletion induces large scale domain segregation in living cell membranes.Role of membrane organization and membrane domains in endocytic lipid trafficking.Cholesterol depletion suppresses the translational diffusion of class II major histocompatibility complex proteins in the plasma membrane.Phospholipase d promotes lipid microdomain-associated signaling events in mast cells.Cholesterol depletion induces solid-like regions in the plasma membrane.Glycyrrhetic acid synergistically enhances β₂-adrenergic receptor-Gs signaling by changing the location of Gαs in lipid rafts.A mechanistic model of early FcεRI signaling: lipid rafts and the question of protection from dephosphorylation.
P2860
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P2860
Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Critical role for cholesterol ...... detergent-resistant membranes
@ast
Critical role for cholesterol ...... detergent-resistant membranes
@en
Critical role for cholesterol ...... detergent-resistant membranes
@nl
type
label
Critical role for cholesterol ...... detergent-resistant membranes
@ast
Critical role for cholesterol ...... detergent-resistant membranes
@en
Critical role for cholesterol ...... detergent-resistant membranes
@nl
prefLabel
Critical role for cholesterol ...... detergent-resistant membranes
@ast
Critical role for cholesterol ...... detergent-resistant membranes
@en
Critical role for cholesterol ...... detergent-resistant membranes
@nl
P2093
P2860
P3181
P356
P1476
Critical role for cholesterol ...... detergent-resistant membranes
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.145.4.877
P407
P577
1999-05-17T00:00:00Z