Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members - Wikidata - wikimedia - TriplyDB

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

http://www.wikidata.org/entity/Q24683254

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Circulating fibroblast growth factor 21 levels are closely associated with hepatic fat content: a cross-sectional study Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21 Liver-specific activities of FGF19 require Klotho beta FGF21 N- and C-termini play different roles in receptor interaction and activation The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition Chronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 release Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes Endocrine fibroblast growth factors 15/19 and 21: from feast to famine FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player?Fibroblast growth factor 21: from pharmacology to physiology Fibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan Crosstalk Fibroblast Growth Factor Signaling in Metabolic Regulation Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and Cancer Regulation and function of the FGF23/klotho endocrine pathways Novel aspects of brown adipose tissue biology Fibroblast growth factor signaling in the vasculature Exploring mechanisms of FGF signalling through the lens of structural biology Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1 A potential link between phosphate and aging--lessons from Klotho-deficient mice Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology Genetic evidence of serum phosphate-independent functions of FGF-23 on bone A better anti-diabetic recombinant human fibroblast growth factor 21 (rhFGF21) modified with polyethylene glycol Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4 FGF23 promotes renal calcium reabsorption through the TRPV5 channel Human FGF-21 Is a Substrate of Fibroblast Activation Protein The parathyroid is a target organ for FGF23 in rats Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression Therapeutic utilities of fibroblast growth factor 19.FGF21 contributes to neuroendocrine control of female reproduction.

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Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

http://www.wikidata.org/entity/Q24683254

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular insights into the kl ...... th factor 19 subfamily members

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Molecular and Cellular Biology

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Molecular insights into the kl ...... th factor 19 subfamily members

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Andrew Beenken

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Anna V Eliseenkova

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Beate Lanske

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ChongFeng Xu

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Fuming Zhang

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Hiroshi Kurosu

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Juliya Kalinina

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Kenneth E White

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Makoto Kuro-o

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Masaya Yamamoto

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P2860

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

FGF-21 as a novel metabolic regulator.

Fibroblast growth factors

Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis

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3417-28

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scholarly article

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1481499

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10.1128/MCB.02249-06

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9

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27

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Moosa Mohammadi

Robert J. Linhardt

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2007-05-01T00:00:00Z

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6468100

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17339340

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1899957

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