Developing a programmed restriction endonuclease for highly specific DNA cleavage - Wikidata - wikimedia - TriplyDB

Developing a programmed restriction endonuclease for highly specific DNA cleavage

Developing a programmed restriction endonuclease for highly specific DNA cleavage

http://www.wikidata.org/entity/Q24812943

about

Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities Homing endonucleases: DNA scissors on a mission Controlling the enzymatic activity of a restriction enzyme by light.Molecular scissors under light control.Triplex technology in studies of DNA damage, DNA repair, and mutagenesis Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.TALE-PvuII fusion proteins--novel tools for gene targeting.Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Chemical modification of Ce(IV)/EDTA-based artificial restriction DNA cutter for versatile manipulation of double-stranded DNA.Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides Targeted approaches for gene therapy and the emergence of engineered meganucleases.Generation of novel nucleases with extended specificity by rational and combinatorial strategies.Artificial DNA cutters for DNA manipulation and genome engineering.Towards artificial metallonucleases for gene therapy: recent advances and new perspectives.Restriction endonucleases: natural and directed evolution.Redesigning the single-chain variant of the restriction endonuclease PvuII by circular permutation.Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule.Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases.Purification, crystallization, X-ray diffraction analysis and phasing of an engineered single-chain PvuII restriction endonuclease.A novel zinc-finger nuclease platform with a sequence-specific cleavage module.Thermo-switchable activity of the restriction endonuclease SsoII achieved by site-directed enzyme modification.Molecular biology. New tool for genome surgery.Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity.From Bioengineering to CRISPR/Cas9 - A Personal Retrospective of 20 Years of Research in Programmable Genome Targeting.The past and presence of gene targeting: from chemicals and DNA via proteins to RNA.

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P2860

Developing a programmed restriction endonuclease for highly specific DNA cleavage

http://www.wikidata.org/entity/Q24812943

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@ast

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@en

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@nl

type

label

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@ast

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@en

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@nl

prefLabel

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@ast

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@en

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@nl

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Nucleic Acids Research

P1476

Developing a programmed restriction endonuclease for highly specific DNA cleavage

@en

P2093

Alfred Pingoud

http://www.w3.org/2001/XMLSchema#string

András Simoncsits

http://www.w3.org/2001/XMLSchema#string

Kristin Eisenschmidt

http://www.w3.org/2001/XMLSchema#string

Thomas Lanio

http://www.w3.org/2001/XMLSchema#string

Vera Pingoud

http://www.w3.org/2001/XMLSchema#string

Wolfgang Wende

http://www.w3.org/2001/XMLSchema#string

P2860

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

Structure and function of type II restriction endonucleases

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities

REBASE--restriction enzymes and DNA methyltransferases

Four base recognition by triplex-forming oligonucleotides at physiological pH.

Triplex-induced recombination and repair in the pyrimidine motif.

PvuII endonuclease contains two calcium ions in active sites

Structural and biochemical characterization of a new Mg(2+) binding site near Tyr94 in the restriction endonuclease PvuII

Crystal structure of PvuII endonuclease reveals extensive structural homologies to EcoRV

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7039-7047

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scholarly article

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10.1093/NAR/GKI1009

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22

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33

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2005-12-14T00:00:00Z

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7413149

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16356926

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1316111

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