JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs.
about
Multiple functions of microsomal triglyceride transfer proteinDiscovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary studyEffect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats.An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionLDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectivesGuinea pigs: a suitable animal model to study lipoprotein metabolism, atherosclerosis and inflammation.Familial hypercholesterolemia: current treatment and advances in management.The chylomicron: relationship to atherosclerosis.Quercetin represses apolipoprotein B expression by inhibiting the transcriptional activity of C/EBPβ.Camphene, a Plant Derived Monoterpene, Exerts Its Hypolipidemic Action by Affecting SREBP-1 and MTP ExpressionCholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia.MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises?Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs.New approaches to target microsomal triglyceride transfer protein.Advancing therapy for hypercholesterolemia.Atherosclerosis, diabetes and lipoproteins.Emerging options in the treatment of dyslipidemias: a bright future?Animal models for the atherosclerosis research: a review.Inhibition of cholesterol absorption: targeting the intestine.Potential approaches to ameliorate hepatic fat accumulation seen with MTP inhibition.Investigational therapies for the treatment of atherosclerosis.Microsomal transfer protein (MTP) inhibition-a novel approach to the treatment of homozygous hypercholesterolemia.Combination therapy of an intestine-specific inhibitor of microsomal triglyceride transfer protein and peroxisome proliferator-activated receptor γ agonist in diabetic ratTargeting microsomal triglyceride transfer protein and lipoprotein assembly to treat homozygous familial hypercholesterolemia.Investigational therapies for hypercholesterolemia.Gene expression profiles in human HepG2 cells treated with extracts of the Tamarindus indica fruit pulp.Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing.Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia.
P2860
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P2860
JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
JTT-130, a microsomal triglyce ...... c triglycerides in guinea pigs
@nl
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@ast
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@en
type
label
JTT-130, a microsomal triglyce ...... c triglycerides in guinea pigs
@nl
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@ast
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@en
prefLabel
JTT-130, a microsomal triglyce ...... c triglycerides in guinea pigs
@nl
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@ast
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@en
P2093
P2860
P356
P1476
JTT-130, a microsomal triglyce ...... triglycerides in guinea pigs.
@en
P2093
Dimple Aggarwal
Kristy L West
Marcela Vergara-Jimenez
Maria Luz Fernandez
Sudeep Shrestha
Tosca L Zern
P2860
P2888
P356
10.1186/1471-2261-5-30
P407
P577
2005-09-27T00:00:00Z
P5875
P6179
1040179019