Functional coverage of the human genome by existing structures, structural genomics targets, and homology models.
about
The RCSB PDB information portal for structural genomics.SAHG, a comprehensive database of predicted structures of all human proteinsDisProt: the Database of Disordered ProteinsThe SWISS-MODEL Repository: new features and functionalitiesMODBASE: a database of annotated comparative protein structure models and associated resources.Quantifying the molecular origins of opposite solvent effects on protein-protein interactionsFunctional impact of missense variants in BRCA1 predicted by supervised learningIn silico elucidation of the molecular mechanism defining the adverse effect of selective estrogen receptor modulatorsDrug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitorsKnowledge-based fragment binding predictionAn association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretationThe evolution of protein structures and structural ensembles under functional constraint.Exploring the structure and function paradigm.Algorithmic approaches to protein-protein interaction site prediction.The utility of geometrical and chemical restraint information extracted from predicted ligand-binding sites in protein structure refinement1,000 structures and more from the MCSG.A new approach to assess and predict the functional roles of proteins across all known structuresExploiting protein flexibility to predict the location of allosteric sitesA comprehensive system for evaluation of remote sequence similarity detectionInteraction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structureFold designability, distribution, and diseaseThe many faces of protein-protein interactions: A compendium of interface geometry.3D complex: a structural classification of protein complexesAssessing the structural conservation of protein pockets to study functional and allosteric sites: implications for drug discoveryEvolutionary trace annotation of protein function in the structural proteome.Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISM.Structure-based systems biology for analyzing off-target bindingMolecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing.Transcreener: screening enzymes involved in covalent regulation.Targeting the human cancer pathway protein interaction network by structural genomics.A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discoveryPhylogenetic assessment of alignments reveals neglected tree signal in gaps.Coverage of whole proteome by structural genomics observed through protein homology modeling database.Automated functional classification of experimental and predicted protein structures.Building macromolecular assemblies by information-driven docking: introducing the HADDOCK multibody docking server.QSCOP-BLAST--fast retrieval of quantified structural information for protein sequences of unknown structure.On the origins of drug polypharmacology
P2860
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P2860
Functional coverage of the human genome by existing structures, structural genomics targets, and homology models.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Functional coverage of the hum ...... s targets, and homology models
@nl
Functional coverage of the hum ...... targets, and homology models.
@ast
Functional coverage of the hum ...... targets, and homology models.
@en
type
label
Functional coverage of the hum ...... s targets, and homology models
@nl
Functional coverage of the hum ...... targets, and homology models.
@ast
Functional coverage of the hum ...... targets, and homology models.
@en
prefLabel
Functional coverage of the hum ...... s targets, and homology models
@nl
Functional coverage of the hum ...... targets, and homology models.
@ast
Functional coverage of the hum ...... targets, and homology models.
@en
P2860
P50
P1476
Functional coverage of the hum ...... targets, and homology models.
@en
P2860
P356
10.1371/JOURNAL.PCBI.0010031
P407
P577
2005-08-19T00:00:00Z