Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
about
Quadruplex DNA: sequence, topology and structureStructure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formationStructure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequenceSolution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequenceSolution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug DesignSolution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loopsSolution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexesMetal Cations in G-Quadruplex Folding and StabilityStructure and stability of human telomeric G-quadruplex with preclinical 9-amino acridinesAn RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It RegulatesIntramolecular DNA quadruplexes with different arrangements of short and long loopsA sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes.Molecular models for intrastrand DNA G-quadruplexes.Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay.U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence.In vitro footprinting of promoter regions within supercoiled plasmid DNA.Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizersAltered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expressionG Quadruplex in Plants: A Ubiquitous Regulatory Element and Its Biological Relevance.Structural insights into G-quadruplexes: towards new anticancer drugs.Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.Secondary structure at a hot spot for DNA methylation in DNA from human breast cancers.Targeting MYC Expression through G-Quadruplexes.Novel G-quadruplex stabilizing agents: in-silico approach and dynamics.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression.Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes.Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor geneHuman telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.Aptamer selection based on G4-forming promoter region.The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements.Structure-based drug design: from nucleic acid to membrane protein targets.NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter regionSmall molecules targeting c-Myc oncogene: promising anti-cancer therapeutics
P2860
Q22065978-F3AB394F-3001-48DF-A8FF-AFB9ADE748CCQ27644282-22831ABA-2893-4BB6-96C6-2248773E58E2Q27646647-B18EBA25-C9DF-4BAE-922C-0A719F6D8D25Q27667674-F062A5DA-A9DD-4CCE-B71D-995540258039Q27674707-913B0FBE-94D7-4A37-A3A1-54814DAEDEB0Q27678724-067222C0-2F53-45CD-B88B-B7BE65EE0548Q27679870-8CADEC89-1ACA-433F-958F-7240EE0E672BQ28073017-1579D892-2A59-4459-9B1C-8097121011FDQ28488110-893EF2A9-85E4-4213-82B9-F4DCFF7A4FE0Q28592449-B4B36149-3CEA-479A-8D5D-0CBC80E2D43FQ29300196-66EFC0A6-6E53-427E-A383-DBC9C00F82CFQ33311334-71943211-E3BF-48BA-B787-1F7EF3D96C47Q33509185-4DF8F753-CF16-4C17-A392-F595C8B94972Q33554873-4DE85B27-9B57-4F6C-97D3-B02898B993DFQ33558251-C91A539C-E892-456D-83BC-F774102D8956Q33594169-EE0A44E6-FA78-4369-A943-DCB6CB4AA3A5Q33652068-7B2E9677-EC42-4159-B5F2-B3D29B6429EEQ33700136-B8637BC0-5BE3-4877-86E3-929E46C588EBQ33843587-F2DDFD53-CF29-4691-B9B4-B08864260483Q33867119-DCF6CCC1-9867-43FD-AAD0-9160285AF131Q33915919-73797AE8-903A-46D5-8851-233DCE1F31ECQ34005475-CAAF2B3E-BD5D-4D9B-9A81-575BB395C981Q34011118-F636F607-6189-4F99-917D-77EFDD72395AQ34043354-4B4C7784-F55B-4370-A630-F9CB62BDB2C0Q34174883-9960E5E4-75AD-482D-B99F-6D6B065FBBB8Q34298087-F1A6DC4C-937C-455A-9D9F-6B8D87F15A09Q34339023-8C941E58-9C31-4B62-A606-C6B05C290D4BQ34352558-8500C685-C624-4010-9F45-66CBBC01B893Q34514081-B1DA4A25-F138-4B81-85F9-F01E6F9ECD61Q34551196-EA9056F9-E526-4818-9C9B-517644CAD376Q34568024-5AE7E9F2-8DE6-43D0-BE18-71E291631A26Q34603183-16C56880-CBA0-45A4-B9E1-8CC2BD81749BQ34609291-8F0DB7BF-3D68-4D41-83EC-C3C86D03D5C5Q34623697-A149DC5F-8CC2-49BB-97D4-8386F5458507Q34764323-7632D3BD-0582-4F6C-9811-048A33A2D6EFQ35126113-81393B9C-130D-4E3F-AE9F-08677C4EA46DQ35127680-C06CA1F5-7375-4C49-A5F8-D1CF8D385636Q35130452-1AFD3605-3B45-4626-92FF-A10983D8585BQ35198333-0506354E-78D1-4331-8524-731819159A4EQ35353405-5B909B12-2797-4E1C-9F35-6CA584DDD59D
P2860
Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Facilitation of a structural t ...... -quadruplex-interactive agents
@nl
Facilitation of a structural t ...... quadruplex-interactive agents.
@ast
Facilitation of a structural t ...... quadruplex-interactive agents.
@en
type
label
Facilitation of a structural t ...... -quadruplex-interactive agents
@nl
Facilitation of a structural t ...... quadruplex-interactive agents.
@ast
Facilitation of a structural t ...... quadruplex-interactive agents.
@en
prefLabel
Facilitation of a structural t ...... -quadruplex-interactive agents
@nl
Facilitation of a structural t ...... quadruplex-interactive agents.
@ast
Facilitation of a structural t ...... quadruplex-interactive agents.
@en
P2093
P2860
P3181
P356
P1476
Facilitation of a structural t ...... quadruplex-interactive agents.
@en
P2093
Daekyu Sun
Jadrian J Rusche
Kexiao Guo
Laurence H Hurley
P2860
P304
P3181
P356
10.1093/NAR/GKI917
P407
P577
2005-10-20T00:00:00Z