mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

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Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide The impact of the human DNA topoisomerase II C-terminal domain on activity.The impact of the C-terminal domain on the interaction of human DNA topoisomerase II α and β with DNA.TOP2B: The First Thirty Years

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mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

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2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年论文

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mAMSA resistant human topoisom ...... educed ATP hydrolysis activity

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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mAMSA resistant human topoisom ...... educed ATP hydrolysis activity

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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mAMSA resistant human topoisom ...... educed ATP hydrolysis activity

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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P1476

mAMSA resistant human topoisom ...... duced ATP hydrolysis activity.

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Caroline A Austin

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Chrysoula Leontiou

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Jeremy H Lakey

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Kathryn L Gilroy

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Kay Padget

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Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism

Mutagenesis of E477 or K505 in the B' domain of human topoisomerase II beta increases the requirement for magnesium ions during strand passage

Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

Structure and mechanism of DNA topoisomerase II

The ATPase reaction cycle of yeast DNA topoisomerase II. Slow rates of ATP resynthesis and P(i) release

Phase II study of XR5000 (DACA), an inhibitor of topoisomerase I and II, administered as a 120-h infusion in patients with advanced ovarian cancer

Mutations at arg486 and glu571 in human topoisomerase IIalpha confer resistance to amsacrine: relevance for antitumor drug resistance in human cells

Two differentially spliced forms of topoisomerase IIalpha and beta mRNAs are conserved between birds and humans.

Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.

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1597-1607

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scholarly article

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10.1093/NAR/GKL057

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English

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2006-03-20T00:00:00Z

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7228860

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16549872

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1405819

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mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

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P2860

P2860

mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

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