Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism
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Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencingmAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.Novel insights into mitotic chromosome condensationDrugging topoisomerases: lessons and challengesStructural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA GyraseA naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogsStructural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis MechanismProteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2{middle dot}DNA and Top2{middle dot}RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxesThe difficult case of crystallization and structure solution for the ParC55 breakage-reunion domain of topoisomerase IV from Streptococcus pneumoniaeVoreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase IIDNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial InhibitionCatalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogueEnhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models.A high-throughput fluorescence polarization assay for inhibitors of gyrase BDNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsKThe use of divalent metal ions by type II topoisomerases.Control of the flow properties of DNA by topoisomerase II and its targeting inhibitor.Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa by peptide chip and proteome analysis: a pilot study with colorectal carcinoma patient samples.PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.Potential role for the Metnase transposase fusion gene in colon cancer through the regulation of key genesHow do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II topoisomerasesDNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passageLocal sensing of global DNA topology: from crossover geometry to type II topoisomerase processivityUnique features of apicoplast DNA gyrases from Toxoplasma gondii and Plasmodium falciparum.Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors.A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.Unlocking and opening a DNA gate.Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase IIDNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity.A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility.Supercoiling Effects on Short-Range DNA Looping in E. coli.Mining expression and prognosis of topoisomerase isoforms in non-small-cell lung cancer by using Oncomine and Kaplan-Meier plotterCoupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism.Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes.Phytoestrogens: perpetrators or protectors?Structure and acetyl-lysine recognition of the bromodomain.DNA Topology and Topoisomerases: Teaching a "Knotty" Subject.Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspectiveThe DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
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P2860
Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism
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2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Recent advances in understandi ...... ype II topoisomerase mechanism
@ast
Recent advances in understandi ...... ype II topoisomerase mechanism
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Recent advances in understandi ...... ype II topoisomerase mechanism
@en-gb
Recent advances in understandi ...... ype II topoisomerase mechanism
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type
label
Recent advances in understandi ...... ype II topoisomerase mechanism
@ast
Recent advances in understandi ...... ype II topoisomerase mechanism
@en
Recent advances in understandi ...... ype II topoisomerase mechanism
@en-gb
Recent advances in understandi ...... ype II topoisomerase mechanism
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Recent advances in understandi ...... ype II topoisomerase mechanism
@en
prefLabel
Recent advances in understandi ...... ype II topoisomerase mechanism
@ast
Recent advances in understandi ...... ype II topoisomerase mechanism
@en
Recent advances in understandi ...... ype II topoisomerase mechanism
@en-gb
Recent advances in understandi ...... ype II topoisomerase mechanism
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P3181
P356
P1476
Recent advances in understandi ...... ype II topoisomerase mechanism
@en
P2093
A.J. Schoeffler
J.M. Berger
P3181
P356
10.1042/BST20051465
P407
P577
2005-12-01T00:00:00Z