LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana.
about
Kinases as druggable targets in trypanosomatid protozoan parasitesLeishmania major MPK7 protein kinase activity inhibits intracellular growth of the pathogenic amastigote stage.Molecular cloning and characterization of mitogen-activated protein kinase 2 in Trypanosoma cruziTrypanosoma brucei: Two mitogen activated protein kinase kinases are dispensable for growth and virulence of the bloodstream formModulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase.Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation.Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.Parasite mitogen-activated protein kinases as drug discovery targets to treat human protozoan pathogens.What has proteomics taught us about Leishmania development?Linear B-cell epitope mapping of MAPK3 and MAPK4 from Leishmania braziliensis: implications for the serodiagnosis of human and canine leishmaniasis.Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance.Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.Homology modeling of LmxMPK4 of Leishmania mexicana and virtual screening of potent inhibitors against it.Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects.In Silico Elucidation and Inhibition Studies of Selected Phytoligands Against Mitogen-Activated Protein Kinases of Protozoan Parasites.Joining forces: first application of a rapamycin-induced dimerizable Cre system for conditional null mutant analysis in Leishmania.
P2860
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P2860
LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
LmxMPK4, a mitogen-activated p ...... tigotes of Leishmania mexicana
@nl
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@ast
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@en
type
label
LmxMPK4, a mitogen-activated p ...... tigotes of Leishmania mexicana
@nl
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@ast
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@en
prefLabel
LmxMPK4, a mitogen-activated p ...... tigotes of Leishmania mexicana
@nl
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@ast
LmxMPK4, a mitogen-activated p ...... igotes of Leishmania mexicana.
@en
P2093
P2860
P356
P1433
P1476
LmxMPK4, a mitogen-activated p ...... tigotes of Leishmania mexicana
@en
P2093
Claudia Sander-Juelch
Inga M Melzer
Martin Kruse
Qiong Wang
P2860
P2888
P356
10.1186/1475-9292-4-6
P407
P50
P577
2005-12-29T00:00:00Z
P5875
P6179
1002575467