Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
about
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.The enemy within: Targeting host-parasite interaction for antileishmanial drug discoveryCasein kinase: the triple meaning of a misnomer.A touch of Zen: post-translational regulation of the Leishmania stress response.Casein kinases as potential therapeutic targets.Enzyme Activity Assays for Protein Kinases: Strategies to Identify Active Substrates.Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects.Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit.Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis
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Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 December 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
@cs
name
Pharmacological assessment def ...... y and intracellular infection.
@en
Pharmacological assessment def ...... y and intracellular infection.
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type
label
Pharmacological assessment def ...... y and intracellular infection.
@en
Pharmacological assessment def ...... y and intracellular infection.
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prefLabel
Pharmacological assessment def ...... y and intracellular infection.
@en
Pharmacological assessment def ...... y and intracellular infection.
@nl
P2093
P2860
P50
P356
P1476
Pharmacological assessment def ...... y and intracellular infection.
@en
P2093
Emilie Durieu
Gerald F Späth
Jean François Taly
Laurent Meijer
Nathalie Aulner
Olivier Leclercq
Pascale Pescher
P2860
P304
P356
10.1128/AAC.02022-13
P407
P577
2013-12-23T00:00:00Z