about
Sheena RadfordElton ZeqirajDavid R. WestheadMark HarrisRobin S. BonKavitha ThirumuruganNicola StonehouseWei-Feng XueRichard BaylissSimon G. PatchingAdam NelsonArwen PearsonDejian ZhouPaul A BealesNeil RansonSophia C. GoodchildLars JeukenPeter StockleyAlison E. AshcroftDarren C. TomlinsonAndrew J WilsonEmanuele PaciPeter J KnightStan BurgessMatthew A WatsonMichael E. WebbStephen A. BaldwinLeon F WillisKarl A. HassanColin W G FishwickAlison BakerPeter AdamsJohn BarrAlan BerryAlex BreezeThomas A EdwardsMichael J. McPhersonMatthew G IadanzaBrendan FarrellDavid J. Brockwell
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Probing biomolecular interactions by combining ETD-tandem mass spectrometry with chemical footprinting methodologiesInterrogating the folding and function of membrane proteins by mass spectrometryStructure and dynamics of oligomeric intermediates in amyloid assemblyExploiting the distinctive catalysis of chemically modified enzymesIn vivo selection of bioprocessable biopharmaceuticalsExploiting the structure of integral membrane pyrophosphatasesDynamic mechanisms of FGFR activation in cancer by kinase mutationsThe development and application of complementary biophysical methods enabling the study of biomacromolecular dynamicsThe initiation of mRNA degradation by the direct entry of RNase E and the degradosome with implications for non-nucleolytic gene controlReaction intermediates in the O2 activation mechanism of an extradiol dioxygenase: visualising catalytic protons and active site dynamics in crystalloSuper resolution imaging of protein dynamics and functions in physiology and diseaseInvestigating E. coli cell envelope proteins and processes through colicin intoxicationCompatibility rules for glycosaminoglycan-amyloid interactionsHow do ATP-independent chaperones assist OMP folding and assembly? Insights from mass spectrometry and other approachesMathematical Virology: A new mathematical approach to viral evolution grounded in experimentTesting novel anti-viral strategies in plantsThe roles of the pre-genomic RNA in Hepatitis B Virus nucleocapsid assembly.Global control of rhythmic gene expression by the transcription factor LHYSingle-molecule assays of the assembly/disassembly mechanisms of ssRNA viruses - Tools for screening novel anti-viralsMolecular level regulation of BIP, a central molecular chaperone in the EREnabling ultra-high resolution hydrogen/deuterium exchange for challenging biomedical systems
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description
research centre at the University of Leeds
@en
research centre at the University of Leeds
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research centre at the University of Leeds
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name
Astbury Centre for Structural Molecular Biology
@en
Astbury Centre for Structural Molecular Biology
@en-ca
Astbury Centre for Structural Molecular Biology
@en-gb
type
label
Astbury Centre for Structural Molecular Biology
@en
Astbury Centre for Structural Molecular Biology
@en-ca
Astbury Centre for Structural Molecular Biology
@en-gb
prefLabel
Astbury Centre for Structural Molecular Biology
@en
Astbury Centre for Structural Molecular Biology
@en-ca
Astbury Centre for Structural Molecular Biology
@en-gb
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astburycentre
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Point (-1.55532 53.80385)