about
ATP-driven remodeling of the linker domain in the dynein motorModel of the brain tumor-Pumilio translation repressor complexHeat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication CycleStructure of Pumilio reveals similarity between RNA and peptide binding motifsTranscription corepressor CtBP is an NAD(+)-regulated dehydrogenaseCrystal structure of the SF3 helicase from adeno-associated virus type 2A beta-sheet interaction interface directs the tetramerisation of the Miz-1 POZ domainStructure and RNA binding of the mouse Pumilio-2 Puf domainStructure of theDrosophila melanogasterRab6 GTPase at 1.4 Å resolutionStructure, Function, and Evolution of the Crimean-Congo Hemorrhagic Fever Virus Nucleocapsid ProteinKinked -strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZLRibosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acidNucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerizationCrystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylationExploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologiesCrystallization and characterization of PU.1/IRF-4/DNA ternary complexModeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable.Crystal structure of the catalytic core of human DNA polymerase kappa.Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics.The crystal structure of the Hazara virus nucleocapsid protein.Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction.Selective and potent proteomimetic inhibitors of intracellular protein-protein interactionsProbing Protein Surfaces: QSAR Analysis with Helix Mimetics.Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups.Expression, purification and crystallization of the Crimean-Congo haemorrhagic fever virus nucleocapsid proteinTowards "bionic" proteins: replacement of continuous sequences from HIF-1α with proteomimetics to create functional p300 binding HIF-1α mimics.Helix-mediated protein--protein interactions as targets for intervention using foldamers.Bespoke RNA recognition by Pumilios.ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal ProtectionGenetic Analysis of Physcomitrella patens Identifies ABSCISIC ACID NON-RESPONSIVE, a Regulator of ABA Responses Unique to Basal Land Plants and Required for Desiccation Tolerance.Hypoxia inducible factor (HIF) as a model for studying inhibition of protein-protein interactions.Orthogonal functionalisation of α-helix mimeticsMutagenesis mapping of the protein-protein interaction underlying FusB-type fusidic acid resistance.Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation.Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction.Probing bunyavirus N protein oligomerisation using mass spectrometry.Hydrocarbon constrained peptides - understanding preorganisation and binding affinity.Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions.Co-occupancy of two Pumilio molecules on a single hunchback NRE.Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII.
P50
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P50
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hulumtues
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հետազոտող
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas Edwards
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Thomas Edwards
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Thomas Edwards
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thomas alfred edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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Thomas A Edwards
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P106
P1153
7202395265
P2031
2000-01-01T00:00:00Z
P21
P31
P496
0000-0002-1467-3674