Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
about
Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor traffickingGeneration of induced neuronal cells by the single reprogramming factor ASCL1Functional Properties of Human Stem Cell-Derived Neurons in Health and DiseaseUnderstanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patientsImportance of being Nernst: Synaptic activity and functional relevance in stem cell-derived neuronsFrom "directed differentiation" to "neuronal induction": modeling neuropsychiatric diseaseSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsForward engineering neuronal diversity using direct reprogrammingAn urgent need for experimental animal model of autism in drug development.In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral IschemiaInduced neuronal reprogramming.Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.Electrophysiological profiles of induced neurons converted directly from adult human fibroblasts indicate incomplete neuronal conversion.Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.Probing disorders of the nervous system using reprogramming approaches.Human-induced pluripotent stem cells generated from intervertebral disc cells improve neurologic functions in spinal cord injuryNeuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.The Human Model: Changing Focus on Autism Research.CEND1 and NEUROGENIN2 Reprogram Mouse Astrocytes and Embryonic Fibroblasts to Induced Neural Precursors and Differentiated Neurons.FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.Modeling neurodevelopmental disorders using human pluripotent stem cells.Annual research review: The (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing--unveiling the dark matter.In vivo reprogramming for tissue repair.New approaches for direct conversion of patient fibroblasts into neural cells.Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.Generation of pure GABAergic neurons by transcription factor programming.Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks.Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem Cells.Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening.Mimicking Neuroligin-2 Functions in β-Cells by Functionalized Nanoparticles as a Novel Approach for Antidiabetic Therapy.The zinc finger E-box-binding homeobox 1 (Zeb1) promotes the conversion of mouse fibroblasts into functional neurons.Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
P2860
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P2860
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@ast
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@en
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@nl
type
label
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@ast
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@en
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@nl
prefLabel
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@ast
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@en
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@nl
P2860
P50
P3181
P356
P1476
Neurons generated by direct co ...... sociated neuroligin-3 mutation
@en
P2860
P304
P3181
P356
10.1073/PNAS.1316240110
P407
P577
2013-10-08T00:00:00Z