IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
about
The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceNK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activationIndependent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells.Immune reconstitution 20 years after treatment with alemtuzumab in a rheumatoid arthritis cohort: implications for lymphocyte depleting therapies.In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cellsPGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells.Monocyte/Macrophage: NK Cell Cooperation-Old Tools for New Functions.Immunobiology of the IL-15/IL-15Rα complex as an antitumor and antiviral agent.Developmental and Functional Control of Natural Killer Cells by Cytokines.Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Associations, Outcomes, and Pathobiology-Thirty Years of Progress but Still Much to Be Done.IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development.The negative NK cell maturation checkpoint Foxo1.Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers.The potential and promise of IL-15 in immuno-oncogenic therapies.Phosphoinositide-3-Kinase Signaling in Human Natural Killer Cells: New Insights from Primary Immunodeficiency.Sorafenib paradoxically activates the RAS/RAF/ERK pathway in polyclonal human NK cells during expansion and thereby enhances effector functions in a dose- and time-dependent manner.Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.
P2860
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P2860
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@ast
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@en
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@nl
type
label
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@ast
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@en
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@nl
prefLabel
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@ast
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@en
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@nl
P2093
P2860
P3181
P356
P1476
IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
@en
P2093
Alaa Kassim Ali
Neethi Nandagopal
Seung-Hwan Lee
P2860
P3181
P356
10.3389/FIMMU.2015.00355
P407
P577
2015-01-01T00:00:00Z