Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
about
Systems psychopharmacology: A network approach to developing novel therapiesBiomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory scienceNetwork-based approaches in drug discovery and early developmentStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewMetabolomics and systems pharmacology: why and how to model the human metabolic network for drug discoveryIncorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic DiseasesBridging the gap between clinicians and systems biologists: from network biology to translational biomedical researchA network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of actionTowards structural systems pharmacology to study complex diseases and personalized medicineSimilarities between the Binding Sites of SB-206553 at Serotonin Type 2 and Alpha7 Acetylcholine Nicotinic Receptors: Rationale for Its Polypharmacological ProfileTarNet: An Evidence-Based Database for Natural Medicine ResearchA Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte MetabolismInvestigating core genetic-and-epigenetic cell cycle networks for stemness and carcinogenic mechanisms, and cancer drug design using big database mining and genome-wide next-generation sequencing dataToward an integrated software platform for systems pharmacologyImplications of systemic dysfunction for the etiology of malignancyLeveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology.Harnessing Big Data for Systems PharmacologyMolecular interaction networks in the analyses of sequence variation and proteomics data.Systems biology modeling of omics data: effect of cyclosporine a on the Nrf2 pathway in human renal cellsIdentification of drug-specific pathways based on gene expression data: application to drug induced lung injury.Process Pharmacology: A Pharmacological Data Science Approach to Drug Development and TherapyCarboplatin-induced hematotoxicity among patients with non-small cell lung cancer: Analysis on clinical adverse events and drug-gene interactions.Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.Curation and analysis of multitargeting agents for polypharmacological modeling.Polypharmacology: drug discovery for the future.The primary glomerulonephritides: a systems biology approach.Clarifying off-target effects for torcetrapib using network pharmacology and reverse docking approach.Drug target inference through pathway analysis of genomics data.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.Rule-based multi-scale simulation for drug effect pathway analysis.Insights from systems pharmacology into cardiovascular drug discovery and therapyFXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.Systems pharmacology dissection of multi-scale mechanisms of action for herbal medicines in stroke treatment and prevention.Network measures for chemical library design.A novel systems pharmacology model for herbal medicine injection: a case using Reduning injection.Implementation of quantitative and systems pharmacology in large pharma.Systematic synergy modeling: understanding drug synergy from a systems biology perspective.Oncoproteomics: Trials and tribulations.Logic-Based and Cellular Pharmacodynamic Modeling of Bortezomib Responses in U266 Human Myeloma Cells.A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation.
P2860
Q26750901-4D6802F1-5A75-4A55-8C91-56B21AA28DC8Q26778374-084B3187-671F-48D0-90A0-0B912EF84FBEQ26827940-7B86DBCF-A547-4353-986B-B873FA2AEC94Q27008867-59DCF457-15C4-4704-8269-54C2A0E962D0Q27144251-A72CEF59-2DF9-46C3-85D4-D057665E87A6Q28069705-14E07C4F-D328-4295-8463-E45E337604AEQ28072766-6E56A330-E0BA-4871-AAA8-BD670301FD5AQ28538646-A0232BF5-D83D-44FE-B6BF-C39088D3A6DBQ28538838-FC1AF896-DE55-476C-A54F-E6FBBECC5769Q28547013-B0358398-406D-4427-AEE8-9D9876771B04Q28552085-16B19349-D42A-4208-9F3A-A1DAF5EFE941Q28553224-5B6BBF21-71E2-4761-AD60-D2F24BE27D07Q28597874-578CE413-49C4-4DD2-8039-BDC94E5AF95DQ28650510-8BA47CF3-3CAE-4C76-93D4-4710EC86415AQ28708952-65F87DFC-E387-49FD-BCBF-52EDE144EC27Q28821886-3C421725-1EB0-4064-9812-A04796014287Q28969528-10413289-475F-4C5C-A044-E70C0EE251D2Q30667112-1D8CCA97-C667-4C71-8577-3D787AEB9181Q30833363-C1AE5998-CC34-4844-81F9-FBC841713C1DQ30941816-87802A4F-2917-48D0-BE06-F522357A9735Q31074800-AD0695D2-3827-4A96-95F6-C4B822BEC05AQ33436456-72280693-18B5-4FB5-8689-85C432584BB3Q33767468-7C23BFA5-5B9C-459E-8291-ABD4E7F04AA4Q34222917-22DE9737-69DE-42CE-AA41-269280E3B8E5Q34319906-B717F29A-0D4C-4A9E-8347-D9C684C97CE0Q34462626-3A1DD03F-9E8A-49EE-84E8-845E53D33D60Q34507683-DA6D8889-9DDC-4DB1-BBB6-F7F3BF92E518Q34570294-2D5F29B5-04F2-44F3-BEE9-26C168D69D31Q34646772-D4812DD3-5C4B-458D-86EA-2C1C6C84BF9DQ34659227-695A8240-C9C8-419D-ADC8-425CE816FA1EQ34979129-A47FC95A-B642-4EF6-93C8-F11F39C99D83Q35025312-FB35D75C-1158-4352-B06A-38A080F9692EQ35219375-5B23B183-4BF6-428E-BBAA-449ECB1662D5Q35241159-E6D4226C-DB43-4BDE-AE0D-B22407D15568Q35389260-7FD4E872-2567-41D4-BD7A-0FB7CC3D57EFQ35760137-5357552E-FE5B-4E81-A1D3-A6CA7345ED1EQ35777950-A8DB034F-1366-4C2D-BED6-8909CB683A26Q35827653-B1264881-17F7-4058-B32C-C30E8CF85BDFQ35962054-31A9E12A-0FB6-4E98-951A-B92AF33E71CCQ36009841-CF5310A2-EAC0-41EC-B870-DC0DE9738EC1
P2860
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@ast
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@en
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@nl
type
label
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@ast
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@en
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@nl
prefLabel
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@ast
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@en
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@nl
P2860
P3181
P1476
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
@en
P2093
Ravi Iyengar
P2860
P304
P3181
P356
10.1146/ANNUREV-PHARMTOX-010611-134520
P407
P577
2012-01-01T00:00:00Z