about
The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.Long-term electrical stimulation at ear and electro-acupuncture at ST36-ST37 attenuated COX-2 in the CA1 of hippocampus in kainic acid-induced epileptic seizure rats.Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent.Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticusTherapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticusIntracerebral hemorrhage outcomes following selective blockade or stimulation of the PGE2 EP1 receptor.Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus.FNTM: a server for predicting functional networks of tissues in mouse.Indomethacin treatment prior to pentylenetetrazole-induced seizures downregulates the expression of il1b and cox2 and decreases seizure-like behavior in zebrafish larvae.Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application.Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2.Infections, inflammation and epilepsyAnti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to BedsideDefining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus.Anticonvulsive Effects of Licofelone on Status Epilepticus Induced by Lithium-pilocarpine in Wistar Rats: a Role for Inducible Nitric Oxide Synthase.Staged anticonvulsant screening for chronic epilepsy.Anti-inflammatory drugs in epilepsy: does it impact epileptogenesis?Are big potassium-type Ca(2+)-activated potassium channels a viable target for the treatment of epilepsy?Modulation of neuronal excitability by immune mediators in epilepsy.Neuroinflammatory targets and treatments for epilepsy validated in experimental models.microRNA and Epilepsy.Immunity and Inflammation in Epilepsy.Neuroinflammation and Infection: Molecular Mechanisms Associated with Dysfunction of Neurovascular Unit.Exploring novel AEDs from drugs used for treatment of non-epileptic disorders.Cyclooxygenase-2 in glioblastoma multiforme.A COX/5-LOX Inhibitor Licofelone Revealed Anticonvulsant Properties Through iNOS Diminution in Mice.Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype.Cyclooxygenase-1 as a Potential Therapeutic Target for Seizure Suppression: Evidences from Zebrafish Pentylenetetrazole-Seizure Model.HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-κB signaling pathway.Novel Targets for Developing Antiseizure and, Potentially, Antiepileptogenic Drugs.Commonalities in epileptogenic processes from different acute brain insults: Do they translate?Anticonvulsant Effect of Swertiamarin Against Pilocarpine-Induced Seizures in Adult Male Mice.Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy.Systemic delivery of selective EP1 and EP3 receptor antagonists attenuates pentylenetetrazole-induced seizures in mice.Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy.Aspirin attenuates spontaneous recurrent seizures in the chronically epileptic mice.Mice lacking L-12/15-lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis.Effects of dexamethasone on the Li-pilocarpine model of epilepsy: protection against hippocampal inflammation and astrogliosis.Inflammation: A Network in the Pathogenesis of Status Epilepticus
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Cyclooxygenase-2 in epilepsy
@nl
Cyclooxygenase-2 in epilepsy.
@ast
Cyclooxygenase-2 in epilepsy.
@en
type
label
Cyclooxygenase-2 in epilepsy
@nl
Cyclooxygenase-2 in epilepsy.
@ast
Cyclooxygenase-2 in epilepsy.
@en
prefLabel
Cyclooxygenase-2 in epilepsy
@nl
Cyclooxygenase-2 in epilepsy.
@ast
Cyclooxygenase-2 in epilepsy.
@en
P2093
P2860
P3181
P356
P1433
P1476
Cyclooxygenase-2 in epilepsy
@en
P2093
Asheebo Rojas
Myung-Soon Yang
Nadia Lelutiu
Paoula Gueorguieva
Thota Ganesh
P2860
P3181
P356
10.1111/EPI.12461
P407
P577
2013-11-08T00:00:00Z