about
The role of RecQ helicases in non-homologous end-joiningDifferential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingSenescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complexThe intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.Human RecQ helicases in DNA repair, recombination, and replication.Rothmund-Thomson Syndrome: novel pathogenic mutations and frequencies of variants in the RECQL4 and USB1 (C16orf57) gene.Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase.Evolutionary conservation of the CDK targets in eukaryotic DNA replication initiation.RECQL4 helicase has oncogenic potential in sporadic breast cancers.The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism.Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae.Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.RECQL4 Regulates p53 Function In Vivo During Skeletogenesis.Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction.Rothmund-Thomson Syndrome: Insights from New Patients on the Genetic Variability Underpinning Clinical Presentation and Cancer Outcome.Upregulation of RECQL4 expression predicts poor prognosis in hepatocellular carcinoma.RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrityOverexpression of RECQL4 is associated with poor prognosis in patients with gastric cancer
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
RECQL4 in genomic instability and aging
@ast
RECQL4 in genomic instability and aging
@en
RECQL4 in genomic instability and aging
@nl
type
label
RECQL4 in genomic instability and aging
@ast
RECQL4 in genomic instability and aging
@en
RECQL4 in genomic instability and aging
@nl
prefLabel
RECQL4 in genomic instability and aging
@ast
RECQL4 in genomic instability and aging
@en
RECQL4 in genomic instability and aging
@nl
P2093
P2860
P3181
P1433
P1476
RECQL4 in genomic instability and aging
@en
P2093
Deborah L. Croteau
Dharmendra Kumar Singh
Huiming Lu
Leslie Hoh Ferrarelli
Vilhelm A. Bohr
P2860
P304
P3181
P356
10.1016/J.TIG.2012.08.003
P407
P577
2012-12-01T00:00:00Z