A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

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http://www.wikidata.org/entity/Q26851160

Q26851160

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Unexploited Antineoplastic Effects of Commercially Available Anti-Diabetic Drugs A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy Killing me softly--future challenges in apoptosis research Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation Case-specific potentiation of glioblastoma drugs by pterostilbene Designing a broad-spectrum integrative approach for cancer prevention and treatment.An overview of the role of cancer stem cells in spine tumors with a special focus on chordoma.Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma Biomarkers of resistance to radiation therapy: a prospective study in cervical carcinoma Evolution of malignant glioma treatment: from chemotherapy to vaccines to viruses.Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo.CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.Misfolded proteins: from little villains to little helpers in the fight against cancer.Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide Subchronic toxicological study of two artemisinin derivatives in dogs Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans.Marketed nonsteroidal anti-inflammatory agents, antihypertensives, and human immunodeficiency virus protease inhibitors: as-yet-unused weapons of the oncologists' arsenal.Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis.The role of interleukin-18 in glioblastoma pathology implies therapeutic potential of two old drugs-disulfiram and ritonavir.Emerging targets for glioblastoma stem cell therapy Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics.Suppression of the invasive potential of Glioblastoma cells by mTOR inhibitors involves modulation of NFκB and PKC-α signaling.The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis.Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage.Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy.Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells.Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells.Glioblastoma treatment using perphenazine to block the subventricular zone's tumor trophic functions.Molecularly targeted therapies for recurrent glioblastoma: current and future targets.Toward precision medicine in glioblastoma: the promise and the challenges.Repurposing some older drugs that cross the blood-brain barrier and have potential anticancer activity to provide new treatment options for glioblastoma.Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification.Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells.Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature.Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.

P2860

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P2860

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

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http://www.wikidata.org/entity/Q26851160

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2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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