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The STING pathway and the T cell-inflamed tumor microenvironment

The STING pathway and the T cell-inflamed tumor microenvironment

http://www.wikidata.org/entity/Q27008371

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Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications STING: infection, inflammation and cancer Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure).Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy.Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.Intratumoral immunotherapy for melanoma.The importance of the tumor microenvironment in the therapeutic management of cancer.Towards precision radiotherapy for use with immune checkpoint blockers.Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.Emerging role of immunotherapy in urothelial carcinoma-Immunobiology/biomarkers.Recent advances in immuno-oncology and its application to urological cancers.Nongenetic functions of the genome.Telltale tumor infiltrating lymphocytes (TIL) in oral, head & neck cancer.Improving vaccine efficacy against malignant glioma cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Concise Review: An (Im)Penetrable Shield: How the Tumor Microenvironment Protects Cancer Stem Cells.Lymphotoxin signalling in tertiary lymphoid structures and immunotherapy.Regulating STING in health and disease p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation.An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis.2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons.A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists.Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors.STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy.cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response.Adaptive Resistance to Cancer Immunotherapy.Molecular Biomarkers of Primary and Acquired Resistance to T-Cell-Mediated Immunotherapy in Cancer: Landscape, Clinical Implications, and Future Directions.Established T Cell-Inflamed Tumors Rejected after Adaptive Resistance Was Reversed by Combination STING Activation and PD-1 Pathway Blockade.Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway.NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway.Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment.Mechanisms regulating T-cell infiltration and activity in solid tumors.Small-Molecule Targets in Tumor Immunotherapy Prognostic role of tumor-infiltrating lymphocytes in gastric cancer: A systematic review and meta-analysis

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The STING pathway and the T cell-inflamed tumor microenvironment

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2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年學術文章

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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The STING pathway and the T cell-inflamed tumor microenvironment

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Leticia Corrales

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Seng-Ryong Woo

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Thomas F. Gajewski

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P2860

Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides

Cancer genome landscapes

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma

Prevention of allogeneic fetal rejection by tryptophan catabolism

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Type I interferon response and innate immune sensing of cancer

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

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