Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancer - Wikidata - wikimedia - TriplyDB

Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancer

Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancer

http://www.wikidata.org/entity/Q27021391

about

miR-589-5p inhibits MAP3K8 and suppresses CD90(+) cancer stem cells in hepatocellular carcinoma.Cot kinase plays a critical role in Helicobacter pylori-induced IL-8 expression.Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis.Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice Rituximab or irradiation promotes IL-17 secretion and thereby induces resistance to rituximab or irradiation.Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.The effect of Ganoderma lucidum extract on immunological function and identify its anti-tumor immunostimulatory activity based on the biological network

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P2860

Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancer

http://www.wikidata.org/entity/Q27021391

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

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2015年論文

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2015年论文

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name

Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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type

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

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International Journal of Molecular Sciences

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Tumor progression locus 2 (Tpl ...... ided effects of Tpl2 on cancer

@en

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Do-Hyun Nam

http://www.w3.org/2001/XMLSchema#string

Han Choi

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Hye Lee

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Kyeung Joo

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Creative Commons Attribution

P2860

ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

The tyrosine kinase Syk regulates TPL2 activation signals

Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

COT phosphorylates prolyl-isomerase Pin1 to promote tumorigenesis in breast cancer

Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1

MSK activation and physiological roles

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase

RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration.

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4471-91

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scholarly article

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2586285

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10.3390/IJMS16034471

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25723737

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proto-oncogene proteins

neoplasm proteins

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4394431

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