ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability
about
Proteins interacting with cloning scars: a source of false positive protein-protein interactionsInterleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinaseTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerTpl2 knockout keratinocytes have increased biomarkers for invasion and metastasisRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseMAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomasAltered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout miceThe protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs)ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesCrosstalk in NF-κB signaling pathwaysIκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinasesFunctions of NF-kappaB1 and NF-kappaB2 in immune cell biologyABIN-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actionsA20 inactivation in ocular adnexal MALT lymphoma.p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activationCoordinate regulation of TPL-2 and NF-κB signaling in macrophages by NF-κB1 p105.The NF-kappaB signalling pathway: a therapeutic target in lymphoid malignancies?Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages.IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400Charting protein complexes, signaling pathways, and networks in the immune system.Coordinating TLR-activated signaling pathways in cells of the immune system.The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cellsActivation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains.Ubiquitin in NF-kappaB signaling.Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells.Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.Regulation of NF-κB by deubiquitinases.IκB kinase regulation of the TPL-2/ERK MAPK pathway.Molecular control of the NEMO family of ubiquitin-binding proteins.TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists.The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways.IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2.Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.The interplay between cyclic AMP, MAPK, and NF-κB pathways in response to proinflammatory signals in microglia.Pellino1 is required for interferon production by viral double-stranded RNA.NFKB p105; TPL2 (COT) and ABIN2 form a stable complex
P2860
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P2860
ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@ast
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en-gb
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@nl
type
label
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@ast
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en-gb
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@nl
prefLabel
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@ast
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en-gb
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@nl
P2093
P2860
P1476
ABIN-2 forms a ternary complex ...... al for TPL-2 protein stability
@en
P2093
S J Watton
P2860
P304
P356
10.1128/MCB.24.12.5235-5248.2004
P407
P577
2004-06-01T00:00:00Z