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Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and CognitionGlobal and local missions of cAMP signaling in neural plasticity, learning, and memoryPhosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotidesProof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer's Dementia.Role of the Apt1 protein in polysaccharide secretion by Cryptococcus neoformans.Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.Genome-wide analysis identifies a role for common copy number variants in specific language impairmentPentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson's Disease.De Novo Mutations in PDE10A Cause Childhood-Onset Chorea with Bilateral Striatal LesionsNew perspectives in cyclic nucleotide-mediated functions in the CNS: the emerging role of cyclic nucleotide-gated (CNG) channels.Plant polyphenols in the treatment of age-associated diseases: revealing the pleiotropic effects of icariin by network analysis.Investigational phosphodiesterase inhibitors in phase I and phase II clinical trials for Alzheimer's disease.Can Cyclic Nucleotide Phosphodiesterase Inhibitors Be Drugs for Parkinson's Disease?Inhibition of PDE2A, but not PDE9A, modulates presynaptic short-term plasticity measured by paired-pulse facilitation in the CA1 region of the hippocampus.Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling.Phosphodiesterase 1: A Unique Drug Target for Degenerative Diseases and Cognitive Dysfunction.A novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia.From Age-Related Cognitive Decline to Alzheimer's Disease: A Translational Overview of the Potential Role for Phosphodiesterases.Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo.A novel mutation of PDE8B Gene in a Japanese family with autosomal-dominant striatal degeneration.Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.Theophylline potentiates lipopolysaccharide-induced NO production in cultured astrocytes.Presymptomatic change in microRNAs modulates Tau pathology.Cilostazol disrupts TLR-4, Akt/GSK-3β/CREB, and IL-6/JAK-2/STAT-3/SOCS-3 crosstalk in a rat model of Huntington's disease
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Phosphodiesterases in neurodegenerative disorders
@ast
Phosphodiesterases in neurodegenerative disorders
@en
Phosphodiesterases in neurodegenerative disorders
@nl
type
label
Phosphodiesterases in neurodegenerative disorders
@ast
Phosphodiesterases in neurodegenerative disorders
@en
Phosphodiesterases in neurodegenerative disorders
@nl
prefLabel
Phosphodiesterases in neurodegenerative disorders
@ast
Phosphodiesterases in neurodegenerative disorders
@en
Phosphodiesterases in neurodegenerative disorders
@nl
P2860
P356
P1433
P1476
Phosphodiesterases in neurodegenerative disorders
@en
P2093
Eva Bollen
Jos Prickaerts
P2860
P304
P356
10.1002/IUB.1104
P407
P577
2012-12-01T00:00:00Z