Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
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Regulation of ROCK activity in cancerPathophysiological Functions of Rnd3/RhoERnd3 as a Novel Target to Ameliorate Microvascular LeakageDifferential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion.RAC1 activation mediates Twist1-induced cancer cell migration.Optofluidic integrated cell sorter fabricated by femtosecond lasers.Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104).ROCK1 is a potential combinatorial drug target for BRAF mutant melanomaRhoE promotes metastasis in gastric cancer through a mechanism dependent on enhanced expression of CXCR4.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.Rnd3 regulates lung cancer cell proliferation through notch signalingRnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure.Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.Snail levels control the migration mechanism of mesenchymal tumor cells.Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion.Small Rho GTPases in the control of cell shape and mobility.Rho kinase inhibitors: a patent review (2012 - 2013).Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling.RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-kinase/myosin phosphatase target pathway.RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3K/Akt signaling pathway.Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells.Cross-analysis of gene and miRNA genome-wide expression profiles in human fibroblasts at different stages of transformation.RhoE is required for contact inhibition and negatively regulates tumor initiation and progression.The Rho family member RhoE interacts with Skp2 and is degraded at the proteasome during cell cycle progression.Trading in your spindles for blebs: the amoeboid tumor cell phenotype in prostate cancer.Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition.Cells with stemness features are generated from in vitro transformed human fibroblastsSTAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas
P2860
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P2860
Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
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2010 nî lūn-bûn
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2010 թուականին հրատարակուած գիտական յօդուած
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2010 թվականին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@ast
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@en
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@nl
type
label
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@ast
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@en
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@nl
prefLabel
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@ast
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@en
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@nl
P2860
P50
P3181
P1433
P1476
Reduced expression of the ROCK ...... ial in mesenchymal tumor cells
@en
P2093
Katiuscia Bonezzi
Maurizia Mello-Grand
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0014154
P407
P50
P577
2010-11-30T00:00:00Z