Rac activation and inactivation control plasticity of tumor cell movement
about
NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradationDcas supports cell polarization and cell-cell adhesion complexes in developmentThe WASP and WAVE family proteinsRac and Rho GTPases in cancer cell motility controlNEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migrationMicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasionMYADM regulates Rac1 targeting to ordered membranes required for cell spreading and migration.Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanismRho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarityThe deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationDifferential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasionProinvasion metastasis drivers in early-stage melanoma are oncogenes.NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neuronsCo-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasionOverexpression of CD99 Increases the Migration and Invasiveness of Human Malignant Glioma CellsGain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomaliesCAS proteins in normal and pathological cell growth controlRho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyNEDD9 promotes oncogenic signaling in mammary tumor development.Rho, ROCK and actomyosin contractility in metastasis as drug targetsCell polarity signaling in the plasticity of cancer cell invasivenessNeural crest: The fourth germ layerRho GTPase signalling in cell migrationPhysical view on migration modesAt the leading edge of three-dimensional cell migrationFrom mechanical force to RhoA activationMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionApproaches to manipulating the dimensionality and physicochemical properties of common cellular scaffoldsThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationS1PR2 links germinal center confinement and growth regulationRho GAPs and GEFs: controling switches in endothelial cell adhesionThe role and regulation of blebs in cell migrationRegulation of ROCK activity in cancerBeyond BRAF: where next for melanoma therapy?Routes and mechanisms of extracellular vesicle uptakeTumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkersRho GTPases in collective cell migrationApolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells.Three-dimensional cage-like microscaffolds for cell invasion studies
P2860
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P2860
Rac activation and inactivation control plasticity of tumor cell movement
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Rac activation and inactivation control plasticity of tumor cell movement
@ast
Rac activation and inactivation control plasticity of tumor cell movement
@en
Rac activation and inactivation control plasticity of tumor cell movement
@nl
type
label
Rac activation and inactivation control plasticity of tumor cell movement
@ast
Rac activation and inactivation control plasticity of tumor cell movement
@en
Rac activation and inactivation control plasticity of tumor cell movement
@nl
prefLabel
Rac activation and inactivation control plasticity of tumor cell movement
@ast
Rac activation and inactivation control plasticity of tumor cell movement
@en
Rac activation and inactivation control plasticity of tumor cell movement
@nl
P2093
P50
P3181
P1433
P1476
Rac activation and inactivation control plasticity of tumor cell movement
@en
P2093
Christopher J Marshall
Hugh Paterson
Jessica Ahn
Sophie Pinner
Victoria Sanz-Moreno
P304
P3181
P356
10.1016/J.CELL.2008.09.043
P407
P577
2008-10-31T00:00:00Z