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Vector transmission of leishmania abrogates vaccine-induced protective immunity

Vector transmission of leishmania abrogates vaccine-induced protective immunity

http://www.wikidata.org/entity/Q27316727

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Lights, camera, and action: vertebrate skin sets the stage for immune cell interaction with arthropod-vectored pathogens Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement Recent advances in microscopic techniques for visualizing leukocytes in vivo Post-Genomics and Vaccine Improvement for Leishmania A Review: The Current In Vivo Models for the Discovery and Utility of New Anti-leishmanial Drugs Targeting Cutaneous Leishmaniasis The influence of early neutrophil-Leishmania interactions on the host immune response to infection Is arthropod saliva the achilles' heel of vector-borne diseases?Determinants for the development of visceral leishmaniasis disease Dissemination of a highly virulent pathogen: tracking the early events that define infection Chronic parasitic infection maintains high frequencies of short-lived Ly6C+CD4+ effector T cells that are required for protection against re-infection Differences in immune responses against Leishmania induced by infection and by immunization with killed parasite antigen: implications for vaccine discovery Neutrophils: Between host defence, immune modulation, and tissue injury What's behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity Vaccines for the leishmaniases: proposals for a research agenda Control of malaria and other vector-borne protozoan diseases in the tropics: enduring challenges despite considerable progress and achievements.The yin and yang of leishmaniasis control.Vaccination with a Leishmania infantum HSP70-II null mutant confers long-term protective immunity against Leishmania major infection in two mice models Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice.Site-dependent recruitment of inflammatory cells determines the effective dose of Leishmania major Seasonality and prevalence of Leishmania major infection in Phlebotomus duboscqi Neveu-Lemaire from two neighboring villages in central Mali.Zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process.Leishmaniasis Vaccine: Where are We Today?Infection parameters in the sand fly vector that predict transmission of Leishmania major Vector saliva in vaccines for visceral leishmaniasis: a brief encounter of high consequence?A canine model of experimental infection with Leishmania (L.) mexicana Leishmania amazonensis infection impairs dendritic cell migration from the inflammatory site to the draining lymph node.Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response.KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. major transmitted by its natural vector Phlebotomus duboscqi Leukocytes infiltrate the skin and draining lymph nodes in response to the protozoan Leishmania infantum chagasi.Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis.Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection.Impact of neutrophil-secreted myeloid related proteins 8 and 14 (MRP 8/14) on leishmaniasis progression.Characterization of the early inflammatory infiltrate at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites.Development of Vaccines against Visceral Leishmaniasis Meta-analysis of the effects of insect vector saliva on host immune responses and infection of vector-transmitted pathogens: a focus on leishmaniasis.A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasis.Indigenous microbiota and Leishmaniasis.Induction of protective CD4+ T cell-mediated immunity by a Leishmania peptide delivered in recombinant influenza viruses.The immune response to sand fly salivary proteins and its influence on leishmania immunity Concomitant Immunity Induced by Persistent Leishmania major Does Not Preclude Secondary Re-Infection: Implications for Genetic Exchange, Diversity and Vaccination.

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P2860

Vector transmission of leishmania abrogates vaccine-induced protective immunity

http://www.wikidata.org/entity/Q27316727

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2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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type

label

Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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Vector transmission of leishmania abrogates vaccine-induced protective immunity

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David L Sacks

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Nagila Secundino

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Nicola Kimblin

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Phillip Lawyer

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Shaden Kamhawi

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P2860

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG.

Synthetic glycovaccine protects against the bite of leishmania-infected sand flies.

Corpse clearance defines the meaning of cell death.

Leishmaniasis: current status of vaccine development

Conditions influencing the efficacy of vaccination with live organisms against Leishmania major infection

Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis.

The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically?

Vaccines for leishmaniasis in the fore coming 25 years.

The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development.

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