EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice
about
Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injuryGenome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathyEphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomersDiscovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activityAge-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American grey short-tailed opossum)Behavioral improvement and regulation of molecules related to neuroplasticity in ischemic rat spinal cord treated with PEDF.Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors.Differential gene expression in the EphA4 knockout spinal cord and analysis of the inflammatory response following spinal cord injuryEphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptorEndothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia.A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after strokeBlockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brainCo-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury.Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats.Neuronal adhesion and synapse organization in recovery after brain injury.Fgf2 improves functional recovery-decreasing gliosis and increasing radial glia and neural progenitor cells after spinal cord injury.EphA4 may contribute to microvessel remodeling in the hippocampal CA1 and CA3 areas in a mouse model of temporal lobe epilepsy.Reactive astrogliosis after spinal cord injury-beneficial and detrimental effects.Dopaminergic axon guidance: which makes what?Spinal cord regeneration: where fish, frogs and salamanders lead the way, can we follow?Spinal cord regeneration: lessons for mammals from non-mammalian vertebrates.Therapeutic targeting of EPH receptors and their ligands.Scar-modulating treatments for central nervous system injury.Spinal cord injury and the neuron-intrinsic regeneration-associated gene program.Eph receptors and ephrins: therapeutic opportunities.EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans.Identification of pivotal genes and pathways for spinal cord injury via bioinformatics analysis.FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cordGlycoengineering of EphA4 Fc leads to a unique, long-acting and broad spectrum, Eph receptor therapeutic antagonist.Receptor tyrosine kinases: molecular switches regulating CNS axon regeneration.Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter.Is integration and survival of newborn neurons the bottleneck for effective neural repair by endogenous neural precursor cells?Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration.Unique sensory and motor behavior in Thy1-GFP-M mice before and after spinal cord injury.Three-dimensional reconstruction of corticospinal tract using one-photon confocal microscopy acquisition allows detection of axonal disruption in spinal cord injury.The Ephrin-A5/EphA4 Interaction Modulates Neurogenesis and Angiogenesis by the p-Akt and p-ERK Pathways in a Mouse Model of TLE.Identification of the genomic mutation in Epha4(rb-2J/rb-2J) mice.The Ephrin receptor EphA4 restricts axonal sprouting and enhances branching in the injured mouse optic nerve.
P2860
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P2860
EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice
description
2011 nî lūn-bûn
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2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@ast
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@en
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@nl
type
label
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@ast
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@en
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@nl
prefLabel
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@ast
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@en
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@nl
P2093
P2860
P3181
P1433
P1476
EphA4 blockers promote axonal ...... ing spinal cord injury in mice
@en
P2093
Andrew W Boyd
Fiona Rogers
Mark D Spanevello
Martin Pearse
Perry F Bartlett
Sophie Tajouri
Yona Goldshmit
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0024636
P407
P577
2011-01-01T00:00:00Z