Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity
about
Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolismIntestine-specific deletion of acyl-CoA:monoacylglycerol acyltransferase (MGAT) 2 protects mice from diet-induced obesity and glucose intolerance.Enterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestine.Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.Liver fatty acid-binding protein binds monoacylglycerol in vitro and in mouse liver cytosol.Direct comparison of mice null for liver or intestinal fatty acid-binding proteins reveals highly divergent phenotypic responses to high fat feeding.Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes.Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice.Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice.Decreased enteric fatty acid amide hydrolase activity is associated with colonic inertia in slow transit constipation.A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017).
P2860
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P2860
Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Over-expression of monoacylgly ...... balance, resulting in obesity
@ast
Over-expression of monoacylgly ...... balance, resulting in obesity
@en
Over-expression of monoacylgly ...... balance, resulting in obesity
@nl
type
label
Over-expression of monoacylgly ...... balance, resulting in obesity
@ast
Over-expression of monoacylgly ...... balance, resulting in obesity
@en
Over-expression of monoacylgly ...... balance, resulting in obesity
@nl
prefLabel
Over-expression of monoacylgly ...... balance, resulting in obesity
@ast
Over-expression of monoacylgly ...... balance, resulting in obesity
@en
Over-expression of monoacylgly ...... balance, resulting in obesity
@nl
P2093
P2860
P1433
P1476
Over-expression of monoacylgly ...... balance, resulting in obesity
@en
P2093
Anita Brinker
John D Douglass
Joseph L Dixon
Loredana Quadro
Nashmia Malik
Su-Hyoun Chon
Yin Xiu Zhou
P2860
P304
P356
10.1371/JOURNAL.PONE.0043962
P407
P577
2012-01-01T00:00:00Z