Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency
about
Capitalizing on the autophagic response for treatment of liver disease caused by alpha-1-antitrypsin deficiency and other genetic diseasesAlpha-1-antitrypsin deficiencyTwo New Considerations for Improving the Diagnosis of α1-Antitrypsin Deficiency-Associated Liver DiseaseEnhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.α1-antitrypsin Deficiency: A Misfolded Secretory Protein Variant with Unique Effects on the Endoplasmic Reticulum.Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways.From phenologs to silent suppressors: Identifying potential therapeutic targets for human disease.Activation of the c-Jun N-terminal kinase pathway aggravates proteotoxicity of hepatic mutant Z alpha1-antitrypsin.Autophagy in the liver: functions in health and disease.Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study.Approaches for Studying Autophagy in Caenorhabditis elegans.Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans.
P2860
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P2860
Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency
description
2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@ast
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@en
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@nl
type
label
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@ast
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@en
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@nl
prefLabel
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@ast
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@en
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@nl
P2093
P2860
P1433
P1476
Fluphenazine reduces proteotox ...... alpha-1-antitrypsin deficiency
@en
P2093
Christine Dippold
David H Perlmutter
Gary A Silverman
Joshua A Benson
Linda P O'Reilly
Michael Ewing
Pamela Hale
Stephen C Pak
P2860
P304
P356
10.1371/JOURNAL.PONE.0087260
P407
P577
2014-01-31T00:00:00Z