Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum
about
P2A-Fluorophore Tagging of BRAF Tightly Links Expression to Fluorescence In VivoAbnormal behaviors and developmental disorder of hippocampus in zinc finger protein 521 (ZFP521) mutant miceC-Raf deficiency leads to hearing loss and increased noise susceptibility.Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal development, function and dysfunctionFuture of combination therapy with dabrafenib and trametinib in metastatic melanoma.Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.In-depth phenotyping of lymphoblastoid cells suggests selective cellular vulnerability in Marinesco-Sjögren syndrome.Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment.Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF.
P2860
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P2860
Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@ast
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@en
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@nl
type
label
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@ast
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@en
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@nl
prefLabel
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@ast
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@en
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@nl
P2093
P2860
P3181
P1433
P1476
Ablation of BRaf impairs neuro ...... tal hippocampus and cerebellum
@en
P2093
Attila Braun
Bernhard Nieswandt
Chaomei Xiang
Guadelupe Camarero
Helmut Heinsen
Rudolf Götz
Ulf R Rapp
Verena Pfeiffer
Yina Zhang
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0058259
P407
P50
P577
2013-01-01T00:00:00Z