Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion
about
Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancerAccurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkersLoss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin.Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancerGenomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer.Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer.The Contribution of Cholesterol and Its Metabolites to the Pathophysiology of Breast CancerOverexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance.The interplay between cell signalling and the mevalonate pathway in cancer.Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer".Obesity and Breast Cancer: Current Insights on the Role of Fatty Acids and Lipid Metabolism in Promoting Breast Cancer Growth and Progression.Advances in Precision Medicine: Tailoring Individualized Therapies.The significance of cholesterol and its metabolite, 27-hydroxycholesterol in breast cancer.27-Hydroxycholesterol, an endogenous selective estrogen receptor modulator.Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial.Luminal lncRNAs Regulation by ERα-Controlled Enhancers in a Ligand-Independent Manner in Breast Cancer Cells.Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-scale, Ion-Current-Based Quantitative Proteomics (IonStar).TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.27-hydroxysterol binds ESR1; ESR2Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancerUp-regulation of HOXB cluster genes are epigenetically regulated in tamoxifen-resistant MCF7 breast cancer cells
P2860
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P2860
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Differential epigenetic reprog ...... ynthesis and cellular invasion
@ast
Differential epigenetic reprog ...... ynthesis and cellular invasion
@en
Differential epigenetic reprog ...... ynthesis and cellular invasion
@nl
type
label
Differential epigenetic reprog ...... ynthesis and cellular invasion
@ast
Differential epigenetic reprog ...... ynthesis and cellular invasion
@en
Differential epigenetic reprog ...... ynthesis and cellular invasion
@nl
prefLabel
Differential epigenetic reprog ...... ynthesis and cellular invasion
@ast
Differential epigenetic reprog ...... ynthesis and cellular invasion
@en
Differential epigenetic reprog ...... ynthesis and cellular invasion
@nl
P2093
P2860
P50
P3181
P356
P1476
Differential epigenetic reprog ...... ynthesis and cellular invasion
@en
P2093
Alba Meira
Darren K Patten
Gianmaria Frige
Jennifer H Steel
Laura Woodley
Manikandan Periyasamy
Monica Faronato
Naina Patel
Philippa Darbre
R Charles Coombes
P2860
P2888
P3181
P356
10.1038/NCOMMS10044
P407
P577
2015-11-27T00:00:00Z
P5875
P6179
1030153887