Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells
about
Scientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in CancerMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast CancerThe Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo.Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse ModelsEnantioselective Addition of Bromonitromethane to Aliphatic N-Boc Aldimines Using a Homogeneous Bifunctional Chiral Organocatalyst.Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.Oridonin synergizes with Nutlin-3 in osteosarcoma cells by modulating the levels of multiple Bcl-2 family proteins.Cell Cycle Regulation and Melanoma.Cisplatin-resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib.Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.MDM2 Antagonists Counteract Drug-Induced DNA Damage.Hydroxycamptothecin mediates antiproliferative effects through apoptosis and autophagy in A549 cells.Using avatars to win the fight over BRAF inhibitor resistance.
P2860
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P2860
Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells
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2014 nî lūn-bûn
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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Mdm2 and Aurora Kinase A Inhib ...... mmune Clearance of Tumor Cells
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Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
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Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
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type
label
Mdm2 and Aurora Kinase A Inhib ...... mmune Clearance of Tumor Cells
@nl
Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
@ast
Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
@en
prefLabel
Mdm2 and Aurora Kinase A Inhib ...... mmune Clearance of Tumor Cells
@nl
Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
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Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
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P2093
P2860
P1433
P1476
Mdm2 and aurora kinase a inhib ...... mmune clearance of tumor cells
@en
P2093
Ann Richmond
Anna E Vilgelm
Clinton F Stewart
Colt M McClain
David C Essaka
David C Turner
Jeff S Pawlikowski
Jeffrey A Ecsedy
Jeffrey A Sosman
Jessica Smith
P2860
P304
P356
10.1158/0008-5472.CAN-14-2405
P407
P577
2014-11-14T00:00:00Z