A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles - Wikidata - wikimedia - TriplyDB

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

http://www.wikidata.org/entity/Q27349737

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Gene therapy of inherited retinal degenerations: prospects and challenges Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery Non-toxic retention of nanoceria in murine eyes Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery.Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins.Gene therapy in ophthalmology.A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression.The potential of nanomedicine therapies to treat neovascular disease in the retina.Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDS POD nanoparticles expressing GDNF provide structural and functional rescue of light-induced retinal degeneration in an adult mouse.Gene therapy for PRPH2-associated ocular disease: challenges and prospects The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse.Vector platforms for gene therapy of inherited retinopathies.Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles.AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects.DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging Nanotechnology and nanotoxicology in retinopathy.Gene Therapy of ABCA4-Associated Diseases.Nanoparticle-based technologies for retinal gene therapy Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells.Suprachoroidal electrotransfer: a nonviral gene delivery method to transfect the choroid and the retina without detaching the retina.DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.Retinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS·ROM-1 Protein Complex Formation.Nanoparticle-motivated gene delivery for ophthalmic application Non-viral therapeutic approaches to ocular diseases: An overview and future directions S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases Insights from Genetic Model Systems of Retinal Degeneration: Role of Epsins in Retinal Angiogenesis and VEGFR2 Signaling.Nanoparticle-mediated miR200-b delivery for the treatment of diabetic retinopathy.Toxicity of nanomaterials to the eye.Nanoparticles for retinal gene therapy.Non-viral retinal gene therapy: a review.Polymeric vectors for ocular gene delivery.Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame?Regenerative nanomedicine and the treatment of degenerative retinal diseases.Emerging biotechnological strategies for non-viral antiangiogenic gene therapy.Gene therapy in animal models of autosomal dominant retinitis pigmentosa

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A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

http://www.wikidata.org/entity/Q27349737

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A partial structural and funct ...... th compacted DNA nanoparticles

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A partial structural and funct ...... th compacted DNA nanoparticles

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A partial structural and funct ...... th compacted DNA nanoparticles

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A partial structural and funct ...... th compacted DNA nanoparticles

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Mark J Cooper

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Muna I Naash

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Shannon M Conley

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Steven J Fliesler

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Xue Cai

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Zack Nash

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P2860

A three-base-pair deletion in the peripherin-RDS gene in one form of retinitis pigmentosa

Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse

Safety and efficacy of gene transfer for Leber's congenital amaurosis

A new mathematical model for relative quantification in real-time RT-PCR

Effect of gene therapy on visual function in Leber's congenital amaurosis

Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.

Molecular characterization of the skate peripherin/rds gene: relationship to its orthologues and paralogues

The relationship between opsin overexpression and photoreceptor degeneration.

Efficient non-viral ocular gene transfer with compacted DNA nanoparticles.

Cell fate determination in the vertebrate retina

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