Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase
about
Structures of hepatitis C virus nonstructural proteins required for replicase assembly and functionRobust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells.Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase.Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon ActivitiesIdentification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase ChimerasThe NS3 Helicase and NS5B-to-3'X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 CellsEffects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various GenotypesThe Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 HelicaseHepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitroA Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus PolymeraseHepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 HelicaseNS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate ConcentrationsHelicase inhibitors as specifically targeted antiviral therapy for hepatitis CVisualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCVNsp9 and Nsp10 contribute to the fatal virulence of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China.Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions.The intraviral protein interaction network of hepatitis C virus.The hepatitis C virus core protein can modulate RNA-dependent RNA synthesis by the 2a polymerase.Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies.Hepatitis C Virus NS3 Mediated Microglial Inflammation via TLR2/TLR6 MyD88/NF-κB Pathway and Toll Like Receptor Ligand Treatment Furnished Immune ToleranceEfficient replication of genotype 3a and 4a hepatitis C virus replicons in human hepatoma cells.RNA binding by the NS3 protease of the hepatitis C virusHepatitis C viral protein translation: mechanisms and implications in developing antivirals.Inhibition of dengue virus polymerase by blocking of the RNA tunnelMultiple mutations in hepatitis C virus NS5A domain II are required to confer a significant level of resistance to alisporivirFunctional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.Understanding the structural and energetic basis of inhibitor and substrate bound to the full-length NS3/4A: insights from molecular dynamics simulation, binding free energy calculation and network analysis.HCV NS3 protein helicase domain assists RNA structure conversion.The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate.Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3.Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations.
P2860
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P2860
Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Stimulation of Hepatitis C Vir ...... V RNA-Dependent RNA Polymerase
@nl
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@ast
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@en
type
label
Stimulation of Hepatitis C Vir ...... V RNA-Dependent RNA Polymerase
@nl
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@ast
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@en
prefLabel
Stimulation of Hepatitis C Vir ...... V RNA-Dependent RNA Polymerase
@nl
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@ast
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@en
P2093
P2860
P1433
P1476
Stimulation of hepatitis C vir ...... V RNA-dependent RNA polymerase
@en
P2093
Chen Zhang
Fenghua Yuan
Guangxiang Luo
Ranjith Kumar
Young-Chan Kim
Zhaohui Cai
P2860
P304
P356
10.1128/JVI.79.14.8687-8697.2005
P50
P577
2005-07-01T00:00:00Z