Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
about
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertasesFurin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteinsPC8 [corrected], a new member of the convertase familyAP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulumCytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathwayExpression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular regionStructural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 proteaseTwo independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinIntracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surfaceIsolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytesMutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasiaFurin at the cutting edge: from protein traffic to embryogenesis and diseaseThe role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cellsCompartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutantMechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not foldingProinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furinAlteration of clathrin light chain expression by transfection and gene disruptionThe ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.Heterologous in vivo processing of human preproendothelin 1 into bioactive peptidesProteolytic maturation of protein C upon engineering the mouse mammary gland to express furin.Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike proteinBDNF and activity-dependent synaptic modulationGeneration of structural and functional diversity in furin-like proteins in Drosophila melanogaster by alternative splicing of the Dfur1 geneSecretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1.Furin cleavage potentiates the membrane fusion-controlling intersubunit disulfide bond isomerization activity of leukemia virus Env.Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.The PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments.Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteasesFurin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells.The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis.Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular proteinExpression of mutant ELH prohormones in AtT-20 cells: the relationship between prohormone processing and sorting.The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.Torso-like mediates extracellular accumulation of Furin-cleaved Trunk to pattern the Drosophila embryo terminiIn vivo expression of mutant preproendothelins: hierarchy of processing events but no strict requirement of Trp-Val at the processing sitealpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent.
P2860
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P2860
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
description
1990 nî lūn-bûn
@nan
1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@ast
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@en
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@nl
type
label
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@ast
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@en
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@nl
prefLabel
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@ast
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@en
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@nl
P2093
P2860
P1476
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo
@en
P2093
H L Gibson
P A Bresnahan
P2860
P304
P407
P433
P577
1990-12-01T00:00:00Z