Solution structure of core binding factor beta and map of the CBF alpha binding site
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Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbetaNovel β-Barrel Fold in the Nuclear Magnetic Resonance Structure of the Replicase Nonstructural Protein 1 from the Severe Acute Respiratory Syndrome CoronavirusMutations in the RUNX2 gene in patients with cleidocranial dysplasiaThe RUNX genes: gain or loss of function in cancerMutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunitStructure and Biophysics of CBFβ/RUNX and Its Translocation Products.Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersChemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.Overview of protein structural and functional folds.Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymusOncogenic potential of the RUNX gene family: 'overview'.The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion.Inhibition of RUNX2 transcriptional activity blocks the proliferation, migration and invasion of epithelial ovarian carcinoma cells.Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival.Knockdown of core binding factorβ alters sphingolipid metabolism.CBFß and HIV Infection.Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells.Filamin A-bound PEBP2beta/CBFbeta is retained in the cytoplasm and prevented from functioning as a partner of the Runx1 transcription factor.HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces.RUN-CBFbeta interaction in C. elegans: computational prediction and experimental verification.CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development.Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha.Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA.Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia.
P2860
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P2860
Solution structure of core binding factor beta and map of the CBF alpha binding site
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Solution structure of core binding factor beta and map of the CBF alpha binding site
@ast
Solution structure of core binding factor beta and map of the CBF alpha binding site
@en
Solution structure of core binding factor beta and map of the CBF alpha binding site
@nl
type
label
Solution structure of core binding factor beta and map of the CBF alpha binding site
@ast
Solution structure of core binding factor beta and map of the CBF alpha binding site
@en
Solution structure of core binding factor beta and map of the CBF alpha binding site
@nl
prefLabel
Solution structure of core binding factor beta and map of the CBF alpha binding site
@ast
Solution structure of core binding factor beta and map of the CBF alpha binding site
@en
Solution structure of core binding factor beta and map of the CBF alpha binding site
@nl
P2093
P3181
P356
P1476
Solution structure of core binding factor beta and map of the CBF alpha binding site
@en
P2093
P2888
P3181
P356
10.1038/10670
P577
1999-07-01T00:00:00Z
P5875
P6179
1049718261