X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine - Wikidata - wikimedia - TriplyDB

X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine

X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine

http://www.wikidata.org/entity/Q27620419

about

KH domain: one motif, two folds Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase X-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity †A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropane Evolution of Substrate Specificity within a Diverse Family of / -Barrel-fold Basic Amino Acid Decarboxylases: X-RAY STRUCTURE DETERMINATION OF ENZYMES WITH SPECIFICITY FOR L-ARGININE AND CARBOXYNORSPERMIDINE Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections Identification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysine Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica In-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plants Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities A comprehensive analysis of non-sequential alignments between all protein structures Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase Current concepts in colorectal cancer prevention Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif.Mutational analysis of substrate interactions with the active site of dialkylglycine decarboxylase Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster.Target repurposing for neglected diseases.Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1.The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing.State of the art in African trypanosome drug discovery.Determination of antiprotozoal drug mechanisms by metabolomics approaches.Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.Gene cloning and molecular characterization of lysine decarboxylase from Selenomonas ruminantium delineate its evolutionary relationship to ornithine decarboxylases from eukaryotes.The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical Advantages Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course.Drug target identification using a trypanosome overexpression library.Characterization of an androgen-responsive, ornithine decarboxylase-related protein in mouse kidney.Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in leguminosae.Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1'-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators.Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.Molecular Evolution and Functional Characterization of a Bifunctional Decarboxylase Involved in Lycopodium Alkaloid Biosynthesis.

P2860

Q24625767-0B255E68-5EE9-4D25-B1A0-F2A475694B4C Q27642606-39E16B18-4E36-4BEC-B0EE-51F7ABDD68B0 Q27643838-800CDD87-CB68-49DF-B65E-1AC195AFB988 Q27644349-364C23E6-CC92-4FBA-A5E8-359DDF2782C7 Q27662159-9562C884-CE20-4852-8DB3-D9DA5E7E7FC5 Q27675929-29EA0D30-87DF-4E9D-A1F9-091EED180685 Q27677359-6F4656DC-6293-4BFB-BFCF-EA13EAF66281 Q28365867-A1C9B8C1-3017-44FE-BB9A-B961A2477A38 Q28472105-3F62666C-BD29-4884-98F2-E0359A6B795E Q28474722-CB2C40C5-49D8-46E5-850C-77075AA4D068 Q28481304-D54ADB17-7E9D-4CDD-B85B-1D4B0E7A187F Q28481512-649EB8A0-0EAD-483A-970C-9CCD2C4677EB Q28483069-CF4854DD-5CA5-4003-8DFE-816A80F92F3F Q28732919-5900C956-D145-4FD5-890A-835ED6DFD37E Q28755873-E158B977-0E1F-40C9-ACC5-640B57102CA7 Q29347303-D2BEACFC-5C4E-404E-AF10-533F42102883 Q33724359-E6823700-A669-44F8-B5F7-14F5CC15C3AD Q33883491-ED39178C-A30F-48AA-959F-CA3FD6761888 Q34065803-A994A576-975A-495D-9D0D-1A4158992AF4 Q34112759-493DE04E-A7FF-49BE-BEBD-EDD536663991 Q34366533-986F5B12-8C42-46E1-9B9A-F56BEC86E128 Q35001054-AEEC347D-D3EA-43E4-9313-3DBA7DEA40DE Q35178447-AF1AFEDD-665A-4B4C-ABDF-F716C0A8AC65 Q35635939-4C3F6A67-DAFA-461D-A336-D1FF7B0661D1 Q36128867-6FECA885-D681-4A2F-83B2-35EEDD8E68D2 Q36451580-89262431-79C5-4CD2-BC01-A59A272D9B41 Q37852737-DB77A0EA-044E-4A78-BE76-4F48269E7234 Q38111816-F7383AFB-343C-4CB6-844E-6CF6A6A7D434 Q38126497-8466C9BD-8A90-497E-8EE5-152B3D66E9D7 Q39587997-7F5F0EC3-C610-45E4-A4D1-91E63B13182B Q40423154-BA75568C-94D9-4B6C-9A30-659188EA1E0A Q41095327-B4D544D5-1B11-4B16-A0FB-B2EB14A73F4A Q41860982-0605637B-5C0F-46E4-9593-5DCE972221F6 Q42114206-3FF9399B-57C0-4389-A7D4-66A9CA468F5A Q42334823-72FAFEF9-1760-4119-B63F-870EBC042E10 Q43003172-85F3CBB2-DCA5-463E-BC2C-85F2F7686E7E Q46293533-1BF735F1-34FD-424E-92EE-DB7919C7CB98 Q47804072-08B96C89-93AD-463D-932C-A492349FDA0F Q48150360-E2DBB83B-8B16-41D1-B0B1-44FBAA812E38 Q48199860-95D548B7-5BDD-4F08-B626-E7689ECB8FB9

P2860

X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine

http://www.wikidata.org/entity/Q27620419

description

1999 nî lūn-bûn

@nan

1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@ast

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@en

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@nl

type

label

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@ast

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@en

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@nl

prefLabel

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@ast

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@en

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@nl

P1433

Q27620419-F314D92D-3FF7-4D36-B070-E34B43D9A7FB

P1476

Q27620419-20F4D9B7-E8F5-4A50-A1B6-C3F6F8B8BAF5

P2093

Q27620419-0390EDC3-EB37-4919-B306-BF91CC41C23B

Q27620419-1EB7992E-B12D-4250-9854-79B273FCA109

Q27620419-62967DE9-38ED-4195-8B7A-4887D46668A3

Q27620419-A381C6F3-2ADE-425D-AE95-6859A44A7841

Q27620419-B88116A2-9B50-49AA-B3D2-5DC8C8EB7D53

P304

Q27620419-7FCE92BE-12B6-4106-8F70-67F807BECC3C

P31

Q27620419-C3E76D52-8227-44D6-8866-33A7F9D9413A

P356

Q27620419-6A7E383F-329A-4EF7-A08D-7A1F9C20FD09

P407

Q27620419-F01888B2-FC3A-42E9-B0FF-6410203FB98D

P433

Q27620419-C6041EC8-3CD6-4E2F-9DC8-E6EF8BB2CDD8

P478

Q27620419-9C2BDE4F-4E90-4321-A7A3-10321B36C5F8

P577

Q27620419-A07ED3BD-A1F3-412A-BF33-5D5069C34802

P698

Q27620419-EA1FA251-8908-4CEF-A59F-367CE064EC47

P921

Q27620419-7405CAD7-6785-441F-B8A8-43B90C98BA50

P356

P1433

P1476

X-ray structure of ornithine d ...... alpha-difluoromethylornithine

@en

P2093

A L Osterman

http://www.w3.org/2001/XMLSchema#string

E J Goldsmith

http://www.w3.org/2001/XMLSchema#string

H B Brooks

http://www.w3.org/2001/XMLSchema#string

M A Phillips

http://www.w3.org/2001/XMLSchema#string

N V Grishin

http://www.w3.org/2001/XMLSchema#string

P304

15174-15184

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/BI9915115

http://www.w3.org/2001/XMLSchema#string

P407

P433

46

http://www.w3.org/2001/XMLSchema#string

P478

38

http://www.w3.org/2001/XMLSchema#string

P577

1999-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10563800

http://www.w3.org/2001/XMLSchema#string

P921

Trypanosoma brucei