Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.
about
Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidasePhylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylasesPhospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice.Enantiospecific reassessment of the pharmacokinetics and pharmacodynamics of oral eflornithine against late-stage Trypanosoma brucei gambiense sleeping sickness.Discovery of novel inhibitors of human S-adenosylmethionine decarboxylase based on in silico high-throughput screening and a non-radioactive enzymatic assay.Assessing toxicity in cancer chemoprevention trials: the other side of the coinNutritional and medicinal aspects of D-amino acids.Current bioanalytical methods for pharmacokinetic studies of drugs used in neglected tropical diseases.Difluoromethylornithine in cancer: new advances.Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues.Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical AdvantagesEnantioselective and nonlinear intestinal absorption of eflornithine in the rat.Examination of the new alpha-(2'Z-fluoro)vinyl trigger with lysine decarboxylase: the absolute stereochemistry dictates the reaction course.Does the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition?3-Fluoroaspartate and pyruvoyl-dependant aspartate decarboxylase: exploiting the unique characteristics of fluorine to probe reactivity and binding.Selective regulation of nicotine and polyamines biosynthesis in tobacco cells by enantiomers of ornithine.Synthesis and Deployment of an Elusive Fluorovinyl Cation Equivalent: Access to Quaternary α-(1'-Fluoro)vinyl Amino Acids as Potential PLP Enzyme Inactivators.
P2860
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P2860
Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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2003年學術文章
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name
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@en
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@nl
type
label
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@en
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@nl
prefLabel
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@en
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@nl
P2093
P2860
P356
P1433
P1476
Inhibition of human ornithine ...... rs of difluoromethylornithine.
@en
P2093
Corey Levenson
David E Stringer
Eugene W Gerner
Natalia A Ignatenko
Patrick Shannon
Phillip Yamauchi
Scott Perrin
P2860
P304
P356
10.1042/BJ20030382
P407
P577
2003-10-01T00:00:00Z