Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
about
The ancient Virus World and evolution of cellsStructure and functionality in flavivirus NS-proteins: perspectives for drug designHepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5AProtein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylationDirect interaction between nucleolin and hepatitis C virus NS5BThe modeled structure of the RNA dependent RNA polymerase of GBV-C virus suggests a role for motif E in Flaviviridae RNA polymerases.Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new membersInhibitors of the Hepatitis C Virus Polymerase; Mode of Action and ResistanceTemplate/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase.Template requirements for RNA synthesis by a recombinant hepatitis C virus RNA-dependent RNA polymeraseMutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymeraseA novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with RibonucleotidesSelection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymeraseOligomerization and Cooperative RNA Synthesis Activity of Hepatitis C Virus RNA-Dependent RNA PolymeraseSelection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymeraseCell-free replication of the hepatitis C virus subgenomic replicon.Recombinant viral RdRps can initiate RNA synthesis from circular templates.A structural and primary sequence comparison of the viral RNA-dependent RNA polymerasesProtein-Protein Interactions between Hepatitis C Virus Nonstructural ProteinsHigh-Affinity Aptamers to Subtype 3a Hepatitis C Virus Polymerase Display Genotypic SpecificityCrystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase EnzymeMechanism of action of a pestivirus antiviral compoundIdentification of a C-Terminal Regulatory Motif in Hepatitis C Virus RNA-Dependent RNA Polymerase: Structural and Biochemical AnalysisMolecular Mechanism of a Thumb Domain Hepatitis C Virus Nonnucleoside RNA-Dependent RNA Polymerase InhibitorCrystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionCharacterization of Hepatitis C Virus Subgenomic Replicon Resistance to Cyclosporine In VitroStabilization of Poliovirus Polymerase by NTP Binding and Fingers–Thumb InteractionsDesign, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determinationInhibition of Hepatitis C Virus (HCV) RNA Polymerase by DNA Aptamers: Mechanism of Inhibition of In Vitro RNA Synthesis and Effect on HCV-Infected CellsStructure-function relationships among RNA-dependent RNA polymerasesDevelopment of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase InhibitorsMutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine AStructural and Functional Analysis of Hepatitis C Virus Strain JFH1 PolymeraseThe flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structureThe ins and outs of four-tunneled Reoviridae RNA-dependent RNA polymerasesA mechanism for initiating RNA-dependent RNA polymerizationCrystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymeraseNon-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibitionCrystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft
P2860
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P2860
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
@nl
type
label
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
@nl
prefLabel
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
@nl
P2093
P3181
P1433
P1476
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
@en
P2093
P304
P3181
P356
10.1016/S0969-2126(00)80031-3
P577
1999-11-15T00:00:00Z