Mapping sonic hedgehog-receptor interactions by steric interference
about
The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingHedgehog signaling pathway and its targets for treatment in basal cell carcinomaHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteA sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1Mammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehogReceptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1Sonic hedgehog, apoptosis, and the penis.Neural influences on sonic hedgehog and apoptosis in the rat penis.Sonic hedgehog restricts adhesion and migration of neural crest cells independently of the Patched- Smoothened-Gli signaling pathwayLipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response.Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer.Small-molecule modulators of the Sonic Hedgehog signaling pathway.Sonic Hedgehog as a mediator of long-range signaling.Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition.Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions.Answering a century old riddle: brachydactyly type A1.Hedgehog secretion and signal transduction in vertebrates.Cancer metastasis as disrupted developmental phenotypePatched1 and Patched2 inhibit Smoothened non-cell autonomously.Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.Structural and mechanistic insight into how antibodies inhibit serine proteases.Interactions between Hedgehog proteins and their binding partners come into view.Cancer stem cells and cancer therapy.Dual roles of the Cardin-Weintraub motif in multimeric Sonic hedgehog.An emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactionsTargeting the hedgehog signaling pathway with interacting peptides to Patched-1.Site-specific protein modification to identify the MutL interface of MutH.Functional characterization of sonic hedgehog mutations associated with holoprosencephaly.Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube.Fat hedgehogs, slower or richer?Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated release.Taking the Occam's Razor Approach to Hedgehog Lipidation and Its Role in Development.Sonic hedgehog multimerization: A self-organizing event driven by post-translational modifications?
P2860
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P2860
Mapping sonic hedgehog-receptor interactions by steric interference
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Mapping sonic hedgehog-receptor interactions by steric interference
@ast
Mapping sonic hedgehog-receptor interactions by steric interference
@en
Mapping sonic hedgehog-receptor interactions by steric interference
@nl
type
label
Mapping sonic hedgehog-receptor interactions by steric interference
@ast
Mapping sonic hedgehog-receptor interactions by steric interference
@en
Mapping sonic hedgehog-receptor interactions by steric interference
@nl
prefLabel
Mapping sonic hedgehog-receptor interactions by steric interference
@ast
Mapping sonic hedgehog-receptor interactions by steric interference
@en
Mapping sonic hedgehog-receptor interactions by steric interference
@nl
P2093
P2860
P3181
P356
P1476
Mapping sonic hedgehog-receptor interactions by steric interference
@en
P2093
E A Garber
F R Taylor
K P Williams
P A Boriack-Sjodin
R B Pepinsky
P2860
P304
10995-1001
P3181
P356
10.1074/JBC.275.15.10995
P407
P577
2000-04-14T00:00:00Z