Altering the reaction specificity of eukaryotic ornithine decarboxylase
about
Putrescine biosynthesis in mammalian tissuesCrystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesisX-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibilityX-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity †A structural insight into the inhibition of human and Leishmania donovani ornithine decarboxylases by 1-amino-oxy-3-aminopropaneCrystallographic and biochemical studies revealing the structural basis for antizyme inhibitor functionEvolution of Substrate Specificity within a Diverse Family of / -Barrel-fold Basic Amino Acid Decarboxylases: X-RAY STRUCTURE DETERMINATION OF ENZYMES WITH SPECIFICITY FOR L-ARGININE AND CARBOXYNORSPERMIDINEThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsAntizyme inhibitor 1: a potential carcinogenic moleculeExpression of human arginine decarboxylase, the biosynthetic enzyme for agmatineIdentification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysineBiochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolyticaIn-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plantsPolyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilitiesStructural and functional analysis of cysteine residues in human glutamate decarboxylase 65 (GAD65) and GAD67.The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thalianaDiscovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylaseDeterminants of the differential antizyme-binding affinity of ornithine decarboxylaseSubstituent effects on electrophilic catalysis by the carbonyl group: anatomy of the rate acceleration for PLP-catalyzed deprotonation of glycine.Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates.Biogenic amines and polyamines: similar biochemistry for different physiological missions and biomedical applications.Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.Computational enzymatic catalysis--clarifying enzymatic mechanisms with the help of computers.The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysisBioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases.Characterization of an androgen-responsive, ornithine decarboxylase-related protein in mouse kidney.Protein kinase Cdelta-mediated signal to ornithine decarboxylase induction is independent of skin tumor suppression.Mutation of residues in the coenzyme binding pocket of Dopa decarboxylase. Effects on catalytic properties.Mutation of tyrosine 332 to phenylalanine converts dopa decarboxylase into a decarboxylation-dependent oxidative deaminase.Paramecium bursaria chlorella virus-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylases.Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in leguminosae.Bioinformatic analysis of the fold type I PLP-dependent enzymes reveals determinants of reaction specificity in l-threonine aldolase from Aeromonas jandaei.
P2860
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P2860
Altering the reaction specificity of eukaryotic ornithine decarboxylase
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2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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Altering the reaction specificity of eukaryotic ornithine decarboxylase
@ast
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@en
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@nl
type
label
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@ast
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@en
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@nl
prefLabel
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@ast
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@en
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@nl
P2093
P356
P1433
P1476
Altering the reaction specificity of eukaryotic ornithine decarboxylase
@en
P2093
A L Osterman
E J Goldsmith
H B Brooks
L K Jackson
M A Phillips
P304
P356
10.1021/BI001209S
P407
P577
2000-09-19T00:00:00Z