Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function - Wikidata - wikimedia - TriplyDB

Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function

Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function

http://www.wikidata.org/entity/Q27650167

about

Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma Evolution of Substrate Specificity within a Diverse Family of / -Barrel-fold Basic Amino Acid Decarboxylases: X-RAY STRUCTURE DETERMINATION OF ENZYMES WITH SPECIFICITY FOR L-ARGININE AND CARBOXYNORSPERMIDINE Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution Antizyme inhibitor 1: a potential carcinogenic molecule Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2.Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension.VASCo: computation and visualization of annotated protein surface contacts.Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation.The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification Critical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor.Minimal antizyme peptide fully functioning in the binding and inhibition of ornithine decarboxylase and antizyme inhibitor.Functional roles of the dimer-interface residues in human ornithine decarboxylase.Evidence of a role for antizyme and antizyme inhibitor as regulators of human cancer.Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells.Structural basis of antizyme-mediated regulation of polyamine homeostasis.Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor.Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma.Mammalian polyamine metabolism and function Critical factors determining dimerization of human antizyme inhibitor.Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma.Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor.Polyamines: therapeutic perspectives in oxidative stress and inflammatory diseases.Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.FRETex: a FRET-based, high-throughput technique to analyze protein-protein interactions.Myc, Oncogenic Protein Translation, and the Role of Polyamines.

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P2860

Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function

http://www.wikidata.org/entity/Q27650167

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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type

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Crystallographic and biochemic ...... or antizyme inhibitor function

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Protein Science

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Chaim Kahana

http://www.w3.org/2001/XMLSchema#string

Orly Dym

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Shira Albeck

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Tamar Unger

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Zippy Bercovich

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Zohar Snapir

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P2860

Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases

Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding

Altering the reaction specificity of eukaryotic ornithine decarboxylase

Inference of macromolecular assemblies from crystalline state

Maximum-likelihood density modification

Coot: model-building tools for molecular graphics

ESPript: analysis of multiple sequence alignments in PostScript

Refinement of macromolecular structures by the maximum-likelihood method

Automated main-chain model building by template matching and iterative fragment extension

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scholarly article

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10.1110/PS.073427208

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5

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17

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