The structure of Sky1p reveals a novel mechanism for constitutive activity
about
Structural evolution of the protein kinase-like superfamilyCell stress modulates the function of splicing regulatory protein RBM4 in translation controlBiochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)Serine-arginine protein kinases: a small protein kinase family with a large cellular presenceThe enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1Processive phosphorylation of alternative splicing factor/splicing factor 2Negative regulation of active zone assembly by a newly identified SR protein kinaseStructure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding SiteComparative surface geometry of the protein kinase familyRegulatory domains of Snf1-activating kinases determine pathway specificity.Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.Identification of Gbp2 as a novel poly(A)+ RNA-binding protein involved in the cytoplasmic delivery of messenger RNAs in yeast.Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturationInhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmissionStructurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactionsConservation, variability and the modeling of active protein kinasesTwo nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factorStructural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection.Identification of a nuclear localization motif in the serine/arginine protein kinase PSRPK of physarum polycephalum.Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway.Substrate and docking interactions in serine/threonine protein kinasesICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression.Phosphorylation-dependent differential regulation of plant growth, cell death, and innate immunity by the regulatory receptor-like kinase BAK1.Regulated cellular partitioning of SR protein-specific kinases in mammalian cellsMechanisms regulating the protein kinases of Saccharomyces cerevisiae.Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.Somatic embryogenesis receptor-like kinase 5 in the ecotype Landsberg erecta of Arabidopsis is a functional RD LRR-RLK in regulating brassinosteroid signaling and cell death control.Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localizationCrystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineeringA serendipitous discovery that in situ proteolysis is essential for the crystallization of yeast CPSF-100 (Ydh1p).Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha.The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics.Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1).Regulation of splicing by SR proteins and SR protein-specific kinases.KinView: a visual comparative sequence analysis tool for integrated kinome research.Primary structural features of SR-like protein acinusS govern the phosphorylation mechanism by SRPK2.ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation.Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones.
P2860
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P2860
The structure of Sky1p reveals a novel mechanism for constitutive activity
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The structure of Sky1p reveals a novel mechanism for constitutive activity
@ast
The structure of Sky1p reveals a novel mechanism for constitutive activity
@en
The structure of Sky1p reveals a novel mechanism for constitutive activity
@nl
type
label
The structure of Sky1p reveals a novel mechanism for constitutive activity
@ast
The structure of Sky1p reveals a novel mechanism for constitutive activity
@en
The structure of Sky1p reveals a novel mechanism for constitutive activity
@nl
prefLabel
The structure of Sky1p reveals a novel mechanism for constitutive activity
@ast
The structure of Sky1p reveals a novel mechanism for constitutive activity
@en
The structure of Sky1p reveals a novel mechanism for constitutive activity
@nl
P2093
P356
P1476
The structure of Sky1p reveals a novel mechanism for constitutive activity
@en
P2093
P2888
P304
P356
10.1038/84178
P577
2001-02-01T00:00:00Z
P6179
1051178536