Inhibition of class C beta-lactamases: structure of a reaction intermediate with a cephem sulfone
about
Three decades of beta-lactamase inhibitorsStructural basis for imipenem inhibition of class C beta-lactamases.Comparison of -lactamases of classes A and D: 1.5-A crystallographic structure of the class D OXA-1 oxacillinaseHydrolysis of third-generation cephalosporins by class C beta-lactamases. Structures of a transition state analog of cefotoxamine in wild-type and extended spectrum enzymesStrategic Design of an Effective -Lactamase Inhibitor: LN-1-255, A 6-ALKYLIDENE-2'-SUBSTITUTED PENICILLIN SULFONEAn Antibiotic-Resistance Enzyme from a Deep-Sea BacteriumDesign, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 CarbapenemaseIncreased Structural Flexibility at the Active Site of a Fluorophore-conjugated -Lactamase Distinctively Impacts Its Binding toward Diverse Cephalosporin Antibioticsβ-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of an Unprecedented Stabilized Acyl-EnzymeStructure of the extended-spectrum class C β-lactamase ADC-1 fromAcinetobacter baumanniiStructural basis for the β-lactamase activity of EstU1, a family VIII carboxylesteraseFlexibility Correlation between Active Site Regions Is Conserved across Four AmpC β-Lactamase EnzymesComparative kinetic analysis on thermal degradation of some cephalosporins using TG and DSC dataAntimicrobial activity of beta-lactam antibiotics against clinical pathogens after molecular inclusion in several cyclodextrins. A novel approach to bacterial resistance.Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.Novel metagenome-derived carboxylesterase that hydrolyzes β-lactam antibioticsStructural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase.Designing Irreversible Inhibitors--Worth the Effort?Beta-lactamase inhibitors: evolving compounds for evolving resistance targets.Global dissemination of beta-lactamases mediating resistance to cephalosporins and carbapenems.Potential inhibitory effect of indolizine derivatives on the two enzymes: nicotinamide phosphoribosyltransferase and beta lactamase, a molecular dynamics study.Structural studies of the mechanism for biosensing antibiotics in a fluorescein-labeled β-lactamase.A fluorescein-labeled AmpC β-lactamase allows rapid characterization of β-lactamase inhibitors by real-time fluorescence monitoring of the β-lactamase-inhibitor interactions.
P2860
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P2860
Inhibition of class C beta-lactamases: structure of a reaction intermediate with a cephem sulfone
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@ast
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@en
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@nl
type
label
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@ast
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@en
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@nl
prefLabel
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@ast
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@en
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@nl
P2093
P356
P1433
P1476
Inhibition of class C beta-lac ...... rmediate with a cephem sulfone
@en
P2093
G V Crichlow
J D Buynak
V R Doppalapudi
P304
P356
10.1021/BI010131S
P407
P577
2001-05-29T00:00:00Z