Increased Structural Flexibility at the Active Site of a Fluorophore-conjugated -Lactamase Distinctively Impacts Its Binding toward Diverse Cephalosporin Antibiotics
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Twelve positions in a β-lactamase that can expand its substrate spectrum with a single amino acid substitution.Deletion mutations conferring substrate spectrum extension in the class A β-lactamase.Variations within class-A β-lactamase physiochemical properties reflect evolutionary and environmental patterns, but not antibiotic specificitySubstrate spectrum extension of PenA in Burkholderia thailandensis with a single amino acid deletion, Glu168delModified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases.Crystallographic Snapshots of Class A β-Lactamase Catalysis Reveal Structural Changes That Facilitate β-Lactam Hydrolysis.
P2860
Increased Structural Flexibility at the Active Site of a Fluorophore-conjugated -Lactamase Distinctively Impacts Its Binding toward Diverse Cephalosporin Antibiotics
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2011 nî lūn-bûn
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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
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2011年論文
@zh-mo
2011年論文
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2011年论文
@wuu
name
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@ast
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@en
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@nl
type
label
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@ast
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@en
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@nl
prefLabel
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@ast
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@en
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@nl
P2093
P2860
P356
P1476
Increased Structural Flexibili ...... erse Cephalosporin Antibiotics
@en
P2093
Hong-Kin Yap
Kwok-Chu Chan
Kwok-Yin Wong
Pui-Kin So
Wai-Hong Chung
Wai-Ting Wong
Yanxiang Zhao
Yun-Chung Leung
P2860
P304
P356
10.1074/JBC.M110.198895
P407
P577
2011-09-09T00:00:00Z