Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
about
The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldariusHuman single-stranded DNA binding proteins are essential for maintaining genomic stabilityThe metagenomic telescopeThe Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repairRAD50 and NBS1 form a stable complex functional in DNA binding and tetheringThe human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptideMre11 assembles linear DNA fragments into DNA damage signaling complexesStructure-function analysis of yeast RNA debranching enzyme (Dbr1), a manganese-dependent phosphodiesterase.DNA End Resection: Facts and MechanismsNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeThe crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activityStructural conservation of RecF and Rad50: implications for DNA recognition and RecF functionCrystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA RepairCrystal Structure of Bacillus stearothermophilus UvrA Provides Insight into ATP-Modulated Dimerization, UvrB Interaction, and DNA BindingDNA apurinic-apyrimidinic site binding and excision by endonuclease IVMalonate-bound structure of the glycerophosphodiesterase fromEnterobacter aerogenes(GpdQ) and characterization of the native Fe2+metal-ion preferenceSubstrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenesMre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break RepairSuperoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosisStructural and Functional Characterisation of a Conserved Archaeal RadA Paralog with Antirecombinase ActivityMechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase SoxBA Mycobacterial Cyclic AMP Phosphodiesterase That Moonlights as a Modifier of Cell Wall PermeabilityNbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and RepairStructural and functional analysis of the Lmo2642 cyclic nucleotide phosphodiesterase from Listeria monocytogenesABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break RepairATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complexMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairStructural insights to the metal specificity of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme familyDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesStructure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signalingStructural basis for DNA recognition and nuclease processing by the Mre11 homologue SbcD in double-strand breaks repairEnd-resection at DNA double-strand breaks in the three domains of lifeCompeting roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae.DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.In vivo analysis of cohesin architecture using FRET in the budding yeast Saccharomyces cerevisiae.Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairCondensin and cohesin display different arm conformations with characteristic hinge angles
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P2860
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
description
2001 nî lūn-bûn
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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
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2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
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2001年论文
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name
Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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P50
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Structural biochemistry and in ...... re11 nuclease and Rad50-ATPase
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10.1016/S0092-8674(01)00335-X
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2001-05-01T00:00:00Z